belladonna and opium (B and O Suppositories)

Pharmacy Author:
Medical and Pharmacy Editor:

GENERIC NAME: belladonna and opium

BRAND NAME: B & O Suppositories

DRUG CLASS AND MECHANISM: Belladonna/opium is a man-made narcotic analgesic and anti-spasmodic combination medication. Belladonna relaxes smooth muscles and stops muscle spasms. Opium is converted to morphine which is an opioid pain reliever. Opioids can reduce gastrointestinal motility, propulsion, secretions, and increase gastrointestinal muscle tone. Opioids also stimulate receptors on nerves in the brain to increase the threshold to pain (increasing the amount of stimulation it takes to feel pain) and reduce the perception of pain (the perceived importance of the pain). These effects help in controlling pain and relieving spasms, especially bladder spasms. Belladonna/opium is a controlled substance.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Belladonna/opium is available as rectal suppositories. Each package contains 12 suppositories. They are manufactured in two different strengths:

  • 16.2 mg of belladonna and 30 mg of opium in each suppository.
  • 16.2 mg of belladonna and 60 mg of opium in each suppository.

STORAGE: Store belladonna/opium suppositories at room temperature. Do not refrigerate the suppositories and protect them from moisture during storage.

PRESCRIBED FOR: Belladonna/opium suppositories are used for the relief of moderate to severe pain caused by bladder spasms when non-narcotic pain medications are not effective. They are also used to space intervals between opiate injections.

Medically Reviewed by a Doctor on 7/21/2014



Report Problems to the Food and Drug Administration

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.

Pill Finder Tool

Need help identifying pills and medications?
Use the pill identifier tool on RxList.


Back to Medications Index