beclomethasone dipropionate inhaler (Vanceril) (cont.)

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DOSING: Beclomethasone is used to prevent attacks of asthma and not to treat active attacks of asthma. Doses vary widely. The medication requires continuous use to be effective. Some benefit may be noted as soon as three days after starting treatment, but optimal benefit usually is not seen until after two to three weeks.

DRUG INTERACTIONS: No drug interactions have been described with inhaled beclomethasone.

PREGNANCY: There does not appear to be an increased risk of malformation in children born to mothers exposed to beclomethasone during pregnancy. Additionally, there is no dependency on or withdrawal from the medication.

NURSING MOTHERS: It is not known if beclomethasone is secreted in breast milk. Other medications in this class of medications are secreted into breast milk, but is not known whether the small amounts that appear in milk have any effect on the infant.

SIDE EFFECTS: The most commonly noted side effects associated with inhaled beclomethasone are mild cough or wheezing due to chemical irritation; these effects may be minimized by using an inhaled bronchodilator (e.g., albuterol or Ventolin) prior to the beclomethasone. Oral candidiasis or thrush, a fungal infection of the mouth and throat, can occur in between 1 in 20 and 1 in 8 persons who use beclomethasone. The risk of thrush is greater with higher doses, but the risk in children is lower than in adults. Hoarseness may occur in as few as 1 in 20 or as many as 1 in 2 persons and is due to chemical irritation. A spacer device that can be attached to the inhaler and washing out the mouth with water following each use of beclomethasone reduces the amount of beclomethasone in the mouth and throat and reduces the risk of thrush and hoarseness.

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