becaplermin, Regranex

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Pharmacy Author: Eni Williams, PharmD, PhD
    Eni Williams, PharmD, PhD

    Dr. Eni Williams graduated from Creighton University in 1988 with a B.S. degree in pharmacy and a Doctor of Pharmacy from Howard University in 1994. She also obtained a Ph.D. in Public Policy in 2009 at the University of Maryland, Baltimore County.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

What is the dosage for becaplermin?

The amount of becaplermin that is applied to the ulcer depends on the size of the ulcer. This can be calculated by measuring the greatest length and width of the ulcer and then applying the amount that is recommended by the directions that accompany each tube of becaplermin. The following method is recommended depending on whether the measurements are in inches or centimeters as follows:

  • A 15 g tube length of ulcer x width x 0.6 = length of gel (inches) or length of ulcer x width ÷ 4 = length of gel (cm)
  • A 2 g tube length of ulcer x width x 1.3 = length of gel (inches) or length of ulcer x width ÷ 2 = length of gel (cm)

To apply becaplermin gel, hands should first be thoroughly washed. The tip of the tube should not be allowed to contact the ulcer site or any other surface and thereby become contaminated. The cap on the tube should be closed tightly after each use. The calculated amount of gel should be applied once a day.

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