Barrett's Esophagus Glossary of Terms

Abdomen: The belly , that part of the body that contains all of the structures between the chest and the pelvis . The abdomen is separated anatomically from the chest by the diaphragm , the powerful muscle spanning the body cavity below the lungs .
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Ablation: Removal or excision. Ablation is usually carried out surgically. For example, surgical removal of the thyroid gland (a total thyroidectomy) is ablation of the thyroid. The word ablation comes from the Latin ablatum meaning to carry away.
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Abnormal: Not normal. Deviating from the usual structure, position, condition, or behavior. In referring to a growth, abnormal may mean that it is cancerous or premalignant (likely to become cancer ).
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Acid reflux: A common condition and an abnormal one in which acid in the stomach rises up into the esophagus. This occurs because the valve separating the contents of the stomach from the esophagus does not function properly. See also: GERD.

Adenocarcinoma: A cancer that develops in the lining or inner surface of an organ. More than 95 percent of prostate cancers are adenocarcinoma.
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Adjacent: Lying nearby. Related terms include superjacent, subjacent, and circumjacent. From ad-, near + the Latin jacere, to lie = to lie near.

Alcohol: An organic chemical in which one or more hydroxyl (OH) groups are attached to carbon (C) atoms in place of hydrogen (H) atoms. Common alcohols include ethyl alcohol or ethanol (found in alcoholic beverages), methyl alcohol or methanol (can cause blindness) and propyl alcohol or propanol (used as a solvent and antiseptic ). Rubbing alcohol is a mixture of acetone , methyl isobutyl ketone, and ethyl alcohol. In everyday talk, alcohol usually refers to ethanol as, for example, in wine, beer, and liquor. It can cause changes in behavior and be addictive.
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Anemia: The condition of having less than the normal number of red blood cells or less than the normal quantity of hemoglobin in the blood. The oxygen-carrying capacity of the blood is, therefore, decreased.
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Antagonist: In biochemistry, an antagonist acts against and blocks an action. For example, insulin lowers the level of glucose (sugar) in the blood, whereas another hormone called glucagon raises it; therefore, insulin and glucagon are antagonists.
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Arthritis: Inflammation of a joint. When joints are inflamed they can develop stiffness, warmth, swelling, redness and pain. There are over 100 types of arthritis. (see osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, lupus, gout, pseudogout).

Asthma : A common disorder in which chronic inflammation of the bronchial tubes (bronchi) makes them swell, narrowing the airways. Asthma involves only the bronchial tubes and does not affect the air sacs ( alveoli ) or the lung tissue (the parenchyma of the lung) itself.
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Attention: The ability to focus selectively on a selected stimulus, sustaining that focus and shifting it at will. The ability to concentrate.
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Backbone: The spine. A flexible row of bones stretching from the base of the skull to the tailbone.
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Bacteria: Single-celled microorganisms which can exist either as independent (free-living) organisms or as parasites (dependent upon another organism for life).
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Bacterium: The singular of bacteria.

Barrett esophagus: See: Barrett's esophagus.

Barrett's esophagus : A complication of severe chronic GERD (gastrointestinal reflux disease) involving changes in the cells of the tissue that line the bottom of the esophagus . These esophageal cells become irritated when the contents of the stomach back up (refluxes) and there is a small but definite increased risk of adenocarcinoma ( cancer ) of the esophagus. The diagnosis of Barrett esophagus rests upon seeing (through endoscopy ) a pink esophageal lining ( mucosa ) that extends a short distance (usually less than 2.5 inches) up the esophagus from the gastroesophageal junction and finding intestinal type cells (goblet cells) on biopsy of the lining. Treatment is, in general, essentially the same as for GERD both medically (with acid-suppression drugs) and surgically (with fundoplication ).
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Benign: Not cancer. Not malignant . A benign tumor does not invade surrounding tissue or spread to other parts of the body. A benign tumor may grow but it stays put (in the same place).
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Bile: Bile is a yellow-green fluid that is made by the liver, stored in the gallbladder and passes through the common bile duct into the duodenum where it helps digest fat. The principal components of bile are cholesterol, bile salts, and the pigment bilirubin.
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Biopsy: The removal of a sample of tissue for purposes of diagnosis. (Many definitions of "biopsy" stipulate that the sample of tissue is removed for examination under a microscope. This may or may not be the case. The diagnosis may be achieved by other means such as by analysis of chromosomes or genes.)
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Blood: The familiar red fluid in the body that contains white and red blood cells, platelets, proteins, and other elements. The blood is transported throughout the body by the circulatory system. Blood functions in two directions: arterial and venous. Arterial blood is the means by which oxygen and nutrients are transported to tissues while venous blood is the means by which carbon dioxide and metabolic by-products are transported to the lungs and kidneys, respectively, for removal from the body.

Bronchitis: Inflammation and swelling of the bronchi. Bronchitis can be acute or chronic.
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Burn: Damage to the skin or other body parts caused by extreme heat, flame, contact with heated objects, or chemicals. Burn depth is generally categorized as first, second, or third degree. The treatment of burns depends on the depth, area, and location of the burn, as well as additional factors, such as material that may be burned onto or into the skin. Treatment options range from simply applying a cold pack to emergency treatment to skin grafts.
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Caffeine: A stimulant found naturally in coffee beans, tea leaves, cocoa beans (chocolate) and kola nuts (cola) and added to soft drinks, foods, and medicines. A cup of coffee has 100-250 milligrams of caffeine. Black tea brewed for 4 minutes has 40-100 milligrams. Green tea has one-third as much caffeine as black tea.
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Calcium: A mineral found mainly in the hard part of bones, where it is stored. Calcium is added to bones by cells called osteoblasts and is removed from bones by cells called osteoclasts. Calcium is essential for healthy bones. It is also important for muscle contraction, heart action, nervous system maintenance, and normal blood clotting. Food sources of calcium include dairy foods, some leafy green vegetables such as broccoli and collards, canned salmon, clams, oysters, calcium-fortified foods, and tofu. According to the National Academy of Sciences, adequate intake of calcium is 1,200 milligrams a day (four glasses of milk) for men and women 51 and older, 1,000 milligrams a day for adults 19 through 50, and 1,300 milligrams a day for children 9 through 18. The upper limit for calcium intake is 2.5 grams daily.

Cancer: An abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some cases, to metastasize (spread).
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Cancer of the cervix: See: Cervical cancer.

Cancer symptoms: Abnormal sensations or conditions that persons can notice that are a result of a cancer. It is important to see your doctor for regular checkups and not wait for problems to occur. But you should also know that the following symptoms may be associated with cancer: changes in bowel or bladder habits, a sore that does not heal, unusual bleeding or discharge, thickening or lump in the breast or any other part of the body, indigestion or difficulty swallowing, obvious change in a wart or mole, or nagging cough or hoarseness . These symptoms are not always a sign of cancer. They can also be caused by less serious conditions. Only a doctor can make a diagnosis. It is important to see a doctor if you have any of these symptoms. Don't wait to feel pain. Early cancer often does not cause pain.
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Carcinoma: Cancer that begins in the skin or in tissues that line or cover body organs. For example, carcinoma can arise in the breast , colon, liver, lung, prostate, and stomach.
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Cardiac: Having to do with the heart.
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Cell: The basic structural and functional unit in people and all living things. Each cell is a small container of chemicals and water wrapped in a membrane .
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Cervix: The cervix is the lower, narrow part of the uterus (womb). The uterus, a hollow, pear-shaped organ, is located in a woman's lower abdomen, between the bladder and the rectum. The cervix forms a canal that opens into the vagina, which leads to the outside of the body.

Chemoprevention: The use of natural or laboratory-made substances to prevent a disease such as cancer. The regular use of aspirin is known to reduce the risk of the polyps from which colorectal cancer arises. This is an instance of chemoprevention.
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Chest: The area of the body located between the neck and the abdomen . The chest contains the lungs , the heart and part of the aorta . The walls of the chest are supported by the dorsal vertebrae , the ribs , and the sternum .
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Chest pain: There are many causes of chest pain. One is angina which results from inadequate oxygen supply to the heart muscle. Angina can be caused by coronary artery disease or spasm of the coronary arteries. Chest pain can also be due to a heart attack (coronary occlusion) and other important diseases such as, for example, dissection of the aorta and a pulmonary embolism. Do not try to ignore chest pain and "work (or play) though it." Chest pain is a warning to seek medical attention.

Chocolate: A food or flavoring made from the seeds of the cacao or chocolate tree. Chocolate is rich in flavinoids, compounds that act as antioxidants. Flavinoids may also lower blood pressure and improve blood flow, by regulating the synthesis of nitric oxide, which dilates blood vessels. Flavinoids, like aspirin, help keep platelets from aggregating on vessel walls. Thus, chocolate may have health benefits, provided it is consumed in moderation.
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Chromosomes: The microscopically visible carriers of the genetic material. They are composed of deoxyribonucleic acid (DNA) and proteins and, under a microscope, look like little rods.
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Chronic: This important term in medicine comes from the Greek chronos, time and means lasting a long time.
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Clinical: 1. Having to do with the examination and treatment of patients. 2. Applicable to patients. A laboratory test may be of clinical value (of use to patients).
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Coagulation: In medicine, the clotting of blood. The process by which the blood clots to form solid masses, or clots.
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Colon: The part of the large intestine that runs from the cecum to the rectum as a long hollow tube that serves to remove water from digested food and let the remaining material, solid waste called stool , move through it to the rectum and leave the body through the anus . .
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Colon cancer: A malignancy that arises from the inner lining of the colon . Most, if not all, of these cancers develop from colonic polyps . Removal of these precancerous polyps can prevent colon cancer.
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Colonic: 1. See: Colonic (adjective). 2. See: Colonic (noun).

Colonoscopy: A procedure in which a long flexible viewing tube (a colonoscope) is threaded up through the rectum for the purpose of inspecting the entire colon and rectum and, if there is an abnormality, taking a biopsy of it or removing it. The colonoscopy procedure requires a thorough bowel cleansing to assure a clear view of the lining. Called also coloscopy.

Complication: In medicine, an additional problem that arises following a procedure, treatment or illness and is secondary to it. A complication complicates the situation.
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Condition: The term "condition" has a number of biomedical meanings including the following:

1. An unhealthy state, such as in "this is a progressive condition."
2. A state of fitness, such as "getting into condition."
3. Something that is essential to the occurrence of something else; essentially a "precondition."
4. As a verb: to cause a change in something so that a response that was previously associated with a certain stimulus becomes associated with another stimulus; to condition a person, as in behavioral conditioning.

Cough: A rapid expulsion of air from the lungs typically in order to clear the lung airways of fluids, mucus, or material. Also called tussis.

Cox-2: Cyclooxygenase-2, a protein acts as an enzyme and specifically catalyzes (speeds) the production of certain chemical messengers called prostaglandins. Some of these messengers are responsible for promoting inflammation. When Cox-2 activity is blocked, inflammation is reduced. Unlike cox-1, cox-2 is active only at the site of inflammation, not in the stomach.

Cyclooxygenase: Abbreviated cox. See: Cox-1; Cox-2.

Diagnosis: 1 The nature of a disease ; the identification of an illness. 2 A conclusion or decision reached by diagnosis. The diagnosis is rabies . 3 The identification of any problem. The diagnosis was a plugged IV.
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Dilating: The widening and opening of the cervix caused by uterine contractions.

Disease: Illness or sickness often characterized by typical patient problems (symptoms) and physical findings (signs). Disruption sequence: The events that occur when a fetus that is developing normally is subjected to a destructive agent such as the rubella (German measles) virus.

DNA: Deoxyribonucleic acid. One of two types of molecules that encode genetic information. (The other is RNA . In humans DNA is the genetic material; RNA is transcribed from it. In some other organisms, RNA is the genetic material and, in reverse fashion, the DNA is transcribed from it.)
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Dominant: A genetic trait is considered dominant if it is expressed in a person who has only one copy of that gene. (In genetic terms, a dominant trait is one that is phenotypically expressed in heterozygotes).
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Duodenal: Pertaining to the duodenum, part of the small intestine. As in duodenal ulcer or duodenal biliary drainage.

Duodenum: The first part of the small intestine. The duodenum extends from the pylorus at the bottom of the stomach to the jejunum, the second part of the small intestine. The duodenum is a common site for the formation of peptic ulcers. We often live with words without thinking where they come from or what they originally meant. That is the case for me with the duodenum. For decades, this writer knew the duodenum as a short but troubled sector of the small intestine. Only today did I learn that the duodenum began as the dodeka-daktulon, twelve fingers to the Greeks, who astutely observed that the duodenum is about 12 finger-breadths long. In German, the popular term for duodenum is Zwölffingerdarm, the 12-finger intestine.

Dysphagia: Difficulty in swallowing. Dysphagia is due to problems in nerve or muscle control. It is common, for example, after a stroke . Dysphagia compromises nutrition and hydration and may lead to aspiration pneumonia and dehydration .
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Dysplasia: Abnormal in form. From the Greek dys- (bad, disordered, abnormal) and plassein (to form). For example, retinal dysplasia is abnormal formation of the retina during embryonic development.
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Electrocoagulation: The coagulation (clotting) of tissue using a high-frequency electrical current applied locally with a metal instrument or needle with the aim of stopping bleeding.
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Electrocoagulation: A procedure that uses an electrical current to stop bleeding.

Endoscope: A lighted optical instrument used to get a deep look inside the body and examine organs such as the throat or esophagus. An endoscope can be rigid or flexible.
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Endoscopic ultrasound : Abbreviated EUS. A procedure that combines endoscopy and ultrasound to obtain images and information about the digestive tract and the surrounding tissue and organs. In EUS a small ultrasound transducer is installed on the tip of the endoscope allowing the transducer to get close to the organs inside the body so the resultant ultrasound images are often more accurate and detailed than ones obtained by traditional ultrasound.
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Endoscopy: Endoscopy is a broad term used to described examining the inside of the body using an lighted, flexible instrument called an endoscope. In general, an endoscope is introduced into the body through a natural opening like the mouth or anus. Although endoscopy can include examination of other organs, the most common endoscopic procedures evaluate the esophagus (swallowing tube), stomach, and portions of the intestine.
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Enzyme: A protein (or protein-based molecule) that speeds up a chemical reaction in a living organism. An enzyme acts as catalyst for specific chemical reactions , converting a specific set of reactants (called substrates) into specific products. Without enzymes, life as we know it would not exist.
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Enzymes: Proteins that act as a catalysts in mediating and speeding a specific chemical reaction .
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Epithelial: Relating to the epithelium, the outside layer of cells that covers all the free, open surfaces of the body including the skin, and mucous membranes that communicate with the outside of the body.

Epithelium: The outside layer of cells that covers all the free, open surfaces of the body including the skin, and mucous membranes that communicate with the outside of the body. By contrast the endothelium is the layer of cells lining the closed internal spaces of the body such as the blood vessels and lymphatic vessels (that convey the lymph, a milky fluid).

Esophageal: Pertaining to the esophagus.

Esophageal cancer: A malignant tumor of the esophagus. The risk of cancer of the esophagus is increased by long-term irritation of the esophagus, such as from smoking, heavy alcohol intake, and Barrett esophagitis. The risk of esophageal cancer rises with the number of cigarettes smoked per day and the duration of smoking. A history of radiotherapy to the area, such as for the treatment of breast cancer or lymphoma, also predisposes to esophageal cancer. Very small tumors in the esophagus usually do not cause symptoms. As a tumor grows, the most common symptom is difficulty in swallowing. There may be a feeling of fullness, pressure, or burning as food goes down the esophagus. Problems with swallowing may come and go. At first, they may be noticed mainly when the person eats meat, bread, or coarse foods, such as raw vegetables. As the tumor grows larger and the pathway to the stomach becomes narrower, even liquids can be hard to swallow, and swallowing may be painful. Cancer of the esophagus can also cause indigestion, heartburn, vomiting, and frequent choking on food. Because of these problems, weight loss is common. Esophageal cancer can be diagnosed through a barium X-ray study of the esophagus and endoscopy and biopsy of the tumor. Treatment includes chemotherapy and sometimes surgery. The prognosis (outlook) with esophageal cancer is guarded. At the time of the diagnosis, more than 50% of patients have unresectable (unremovable) tumors or evidence of metastases.

Esophagectomy: An operation to remove a portion of the esophagus.
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Esophagitis: Inflammation of the esophagus. The esophagus is that soft tube-like portion of the digestive tract connecting the pharynx with the stomach.

Esophagus: The tube that connects the pharynx (throat) with the stomach. The esophagus lies between the trachea (windpipe) and the spine. It passes down the neck, pierces the diaphragm just to the left of the midline, and joins the cardiac (upper) end of the stomach. In an adult, the esophagus is about 25 centimeters (10 inches) long. When a person swallows, the muscular walls of the esophagus contract to push food down into the stomach. Glands in the lining of the esophagus produce mucus, which keeps the passageway moist and facilitates swallowing. Also known as the gullet or swallowing tube. From the Greek oisophagos, from oisein meaning to bear or carry + phagein, to eat.

False positive: A result that is erroneously positive when a situation is normal. An example of a false positive: a particular test designed to detect cancer of the toenail is positive but the person does not have toenail cancer.
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Familial: A condition that is tends to occur more often in family members than expected by chance alone. A familial disease may be genetic (such as cystic fibrosis ) or environmental (such as tuberculosis ).
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Familial polyposis: An inherited condition in which several hundred polyps develop in the colon and rectum.

Family: 1. A group of individuals related by blood or marriage or by a feeling of closeness. 2. A biological classification of related plants or animals that is a division below the order and above the genus. 3. A group of genes related in structure and in function that descended from an ancestral gene. 4. A group of gene products similarly related in structure and function and of shared genetic descent. 5. Parents and their children. The most fundamental social group in humans.

Fat: 1 Along with proteins and carbohydrates, one of the three nutrients used as energy sources by the body. The energy produced by fats is 9 calories per gram. Proteins and carbohydrates each provide 4 calories per gram. 2 Total fat; the sum of saturated, monounsaturated and polyunsaturated fats. Intake of monounsaturated and polyunsaturated fats can help reduce blood cholesterol when substituted for saturated fats in the diet. 3 A slang term for obese or adipose. 4 In chemistry, a compound formed from chemicals called fatty acids. These fats are greasy, solid materials found in animal tissues and in some plants. Fats are the major component of the flabby material of a body, commonly known as blubber.

FDA: The Food and Drug Administration, an agency within the U.S. Public Health Service, which is a part of the Department of Health and Human Services.
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Feet: The plural of foot, both an anatomic structure and a unit of measure.
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Female: The traditional definition of female was "an individual of the sex that bears young" or "that produces ova or eggs". However, things are not so simple today. Female can be defined by physical appearance, by chromosome constitution (see Female chromosome complement), or by gender identification. Female chromosome complement: The large majority of females have a 46, XX chromosome complement (46 chromosomes including two X chromosomes). A minority of females have other chromosome constitutions such as 45,X (45 chromosomes including only one X chromosome) and 47,XXX (47 chromosomes including three X chromosomes).

Food and Drug Administration: The FDA, an agency within the U.S. Public Health Service, which is a part of the Department of Health and Human Services.
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Forceps: An instrument with two blades and a handle used for handling, grasping, or compressing. Many types of forceps are employed in medicine, including the alligator forceps (an angled instrument with jaws at the end), tissue forceps (a form of tweezer), hemostatic forceps (also simply called a hemostat, to clamp a bleeding vessel), mosquito forceps (a small hemostat) and obstetrical forceps (to aid in delivering a baby).
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Fundoplication (anti-reflux surgery): A surgical technique that strengthens the barrier to acid reflux when the lower esophageal sphincter does not work normally and there is gastro-esophageal reflux.
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Fundus: Latin word for the bottom. In medicine, fundus refers to the bottom or base of an organ.
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Gastric: Having to do with the stomach.

Gastritis: Inflammation of the stomach. From the Latin gastricus meaning stomach + -itis, meaning inflammation.

Gastroesophageal: Pertaining to both the stomach and the esophagus, as in the gastroesophageal junction, the place where the esophagus connects to the stomach.

Gastroesophageal junction: The junction between the stomach and the esophagus; the place where the esophagus connects to the stomach.

Gastroesophageal reflux: The return of stomach contents back up into the esophagus This frequently causes heartburn because of irritation of the esophagus by stomach acid.
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Gastrointestinal: Adjective referring collectively to the stomach and small and large intestines.
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Gastrointestinal tract: The tube that extends from the mouth to the anus in which the movement of muscles and release of hormones and enzymes digest food. The gastrointestinal tract starts with the mouth and proceeds to the esophagus, stomach, duodenum, small intestine, large intestine (colon), rectum and, finally, the anus. Also called the alimentary canal, digestive tract and, perhaps most often in conversation, the GI tract.

Genes: The basic biological units of heredity . Segments of deoxyribonucleic acid (DNA) needed to contribute to a function.
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GERD: Stands for Gastroesophageal Reflux Disease , a disorder in which there is recurrent return of stomach contents back up into the esophagus, frequently causing heartburn, a symptom of irritation of the esophagus by stomach acid. This can lead to scarring and stricture of the esophagus, which can require stretching (dilating).
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Gland: 1. A group of cells that secrete a substance for use in the body. For example, the thyroid gland. 2. A group of cells that removes materials from the circulation. For example, a lymph gland.

Health: As officially defined by the World Health Organization, a state of complete physical, mental, and social well-being, not merely the absence of disease or infirmity.

Heartburn: An uncomfortable feeling of burning and warmth occurring in waves rising up behind the breastbone (sternum) toward the neck. It is usually due to gastroesophageal reflux disease (GERD), the rise of stomach acid back up into the esophagus. Heartburn has nothing whatsoever to do with the heart. It is a popular nonmedical term. It is medically called pyrosis.

Hernia: A general term referring to a protrusion of a tissue through the wall of the cavity in which it is normally contained.
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Hiatal: Pertaining to an hiatus, an opening.
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Hiatal hernia: An anatomical abnormality in which part of the stomach protrudes up through the diaphragm into the chest .

Host: 1. The organism from which a parasite obtains its nutrition and/or shelter.
2. An organism or cell culture in which a virus can replicate itself.
3. The transplant recipient of a tissue or organ graft.

Incision: A cut. When making an incision, a surgeon is making a cut.

Indicate: In medicine, to make a treatment or procedure advisable because of a particular condition or circumstance. For example, certain medications are indicated for the treatment of hypertension during pregnancy while others are contraindicated.

Infection: The growth of a parasitic organism within the body. (A parasitic organism is one that lives on or in another organism and draws its nourishment therefrom.) A person with an infection has another organism (a "germ") growing within him, drawing its nourishment from the person.
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Inflammation: A basic way in which the body reacts to infection , irritation or other injury, the key feature being redness, warmth, swelling and pain . Inflammation is now recognized as a type of nonspecific immune response .
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Injury: Harm or hurt. The term "injury" may be applied in medicine to damage inflicted upon oneself as in a hamstring injury or by an external agent on as in a cold injury. The injury may be accidental or deliberate, as with a needlestick injury. The term "injury" may be synonymous (depending on the context) with a wound or with trauma.

Intestine: The long, tubelike organ in the abdomen that completes the process of digestion. It consists of the small and large intestines.

Kidney: One of a pair of organs located in the right and left side of the abdomen which clear "poisons" from the blood, regulate acid concentration and maintain water balance in the body by excreting urine. The kidneys are part of the urinary tract. The urine then passes through connecting tubes called "ureters" into the bladder. The bladder stores the urine until it is released during urination.

Laparoscopic: 1. Pertaining to the procedure of laparoscopy .
2. Pertaining to a laparoscope , the instrument by which laparoscopy is done.
3. Performed by laparoscopy.
4. Performed with a laparoscope.
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Laparoscopy: A type of minimally invasive surgery in which a small incision (cut) is made in the abdominal wall through which an instrument called a laparoscope is inserted to permit structures within the abdomen and pelvis to be seen. The abdominal cavity is distended and made visible by the instillation of absorbable gas, typically, carbon dioxide. A diversity of tubes can be pushed through the same incision in the skin. Probes or other instruments can thus be introduced through the same opening. In this way, a number of surgical procedures can be performed without the need for a large surgical incision. Most patients receive general anesthesia during the procedure.
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Larynx: The larynx is the portion of the breathing, or respiratory, tract containing the vocal cords which produce vocal sound. It is located between the pharynx and the trachea. The larynx, also called the voice box, is a 2-inch-long, tube-shaped organ in the neck.

Laser: A powerful beam of light that can produce intense heat when focused at close range. Lasers are used in medicine in microsurgery, cauterization, for diagnostic purposes, etc. For example, lasers are employed in microsurgery to cut tissue and remove tissue.
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Liver: An organ in the upper abdomen that aids in digestion and removes waste products and worn-out cells from the blood. The liver is the largest solid organ in the body. The liver weighs about three and a half pounds (1.6 kilograms). It measures about 8 inches (20 cm) horizontally (across) and 6.5 inches (17 cm) vertically (down) and is 4.5 inches (12 cm) thick.

Lungs: The lungs are a pair of breathing organs located with the chest which remove carbon dioxide from and bring oxygen to the blood. There is a right and left lung.

Malignant: 1. Tending to be severe and become progressively worse, as in malignant hypertension. 2. In regard to a tumor, having the properties of a malignancy that can invade and destroy nearby tissue and that may spread (metastasize) to other parts of the body.
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Marker: A piece of DNA that lies on a chromosome so close to a gene that the marker and the gene are inherited together. A marker is thus an identifiable heritable spot on a chromosome. A marker can be an expressed region of DNA (a gene) or a segment of DNA with no known coding function. All that matters is that the marker can be detected and trailed.
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Medication: 1. A drug or medicine. 2. The administration of a drug or medicine. (Note that "medication" does not have the dangerous double meaning of "drug.")

Microscope: An optical instrument that augments the power of the eye to see small objects. The name microscope was coined by Johannes Faber (1574-1629) who in 1628 borrowed from the Greek to combined micro-, small with skopein, to view. Although the first microscopes were simple microscopes, most (if not all) optical microscopes today are compound microscopes.

Morbidity: Illness, disease.

Mortality: A fatal outcome or, in one word, death. The word "mortality" is derived from "mortal" which came from the Latin "mors" (death). The opposite of mortality is, of course, immortality. Mortality is also quite distinct from morbidity (illness).
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Mouth: 1. The upper opening of the digestive tract, beginning with the lips and containing the teeth, gums, and tongue. Foodstuffs are broken down mechanically in the mouth by chewing and saliva is added as a lubricant. Saliva contains amylase, an enzyme that digests starch. 2. Any opening or aperture in the body. The mouth in both senses of the word is also called the os, the Latin word for an opening, or mouth. The o in os is pronounced as in hope. The genitive form of os is oris from which comes the word oral.

Mucosa: Having to do with a mucous membrane. For example, the oral mucosa.

Muscular: Having to do with the muscles. Also, endowed with above average muscle development. Muscular system refers to all of the muscles of the body collectively.

Nausea: Nausea is the urge to vomit. It can be brought by many causes including, systemic illnesses, such as influenza, medications, pain, and inner ear disease.

Onset: In medicine, the first appearance of the signs or symptoms of an illness as, for example, the onset of rheumatoid arthritis . There is always an onset to a disease but never to the return to good health. The default setting is good health.
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Operation: Although there are many meanings to the word "operation", in medicine it refers to a surgical procedure.
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Overweight: The term "overweight" is used in two different ways. In one sense it is a way of saying imprecisely that someone is heavy. The other sense of "overweight" is more precise and designates a state between normal weight and obesity .
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Pain: An unpleasant sensation that can range from mild, localized discomfort to agony. Pain has both physical and emotional components. The physical part of pain results from nerve stimulation. Pain may be contained to a discrete area, as in an injury, or it can be more diffuse, as in disorders like fibromyalgia . Pain is mediated by specific nerve fibers that carry the pain impulses to the brain where their conscious appreciation may be modified by many factors.
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Pancreas: A fish-shaped spongy grayish-pink organ about 6 inches (15 cm) long that stretches across the back of the abdomen, behind the stomach. The head of the pancreas is on the right side of the abdomen and is connected to the duodenum (the first section of the small intestine). The narrow end of the pancreas, called the tail, extends to the left side of the body.

Pancreatic: Having to do with the pancreas, a spongy, tube-shaped organ about 6 inches long. It is located in the back of the abdomen, behind the stomach. The head of the pancreas is on the right side of the abdomen. It is connected to the duodenum, the upper end of the small intestine. The narrow end of the pancreas, called the tail, extends to the left side of the body.

Pathologist: A doctor who identifies diseases by studying cells and tissues under a microscope.

Photodynamic therapy: A form of cancer treatment using an photosensitizing agent administered intravenously which concentrates selectively in tumor cells, followed by exposure of the tumor tissue to a special red laser light, in order to destroy as much of the tumor as possible.
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Pill: In pharmacy, a medicinal substance in a small round or oval mass meant to be swallowed. Pills often contain a filler and a plastic substance such as lactose that permits the pill to be rolled by hand or machine into the desired form. The pill may then be coated with a varnishlike substance.
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Plasma: The liquid part of the blood and lymphatic fluid, which makes up about half of its volume. Plasma is devoid of cells and, unlike serum, has not clotted. Blood plasma contains antibodies and other proteins. It is taken from donors and made into medications for a variety of blood-related conditions. Some blood plasma is also used in non-medical products.

Postoperative: After surgery. As opposed to preoperative, before surgery.

Premalignant: Pertaining to tissue that is not yet malignant, but is poised to become malignant. Appropriate clinical and laboratory studies are designed to detect premalignant tissue while it is still in a premalignant stages. A large battery of techniques are generally available to remove or kill the tissue, thereby preventing the development of cancer. The proper treatment method depends on the particular premalignant tissue involved. Following are a few examples of premalignant growths:
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Prescription: A physician's order for the preparation and administration of a drug or device for a patient. A prescription has several parts. They include the superscription or heading with the symbol "R" or "Rx", which stands for the word recipe (meaning, in Latin, to take); the inscription, which contains the names and quantities of the ingredients; the subscription or directions for compounding the drug; and the signature which is often preceded by the sign "s" standing for signa (Latin for mark), giving the directions to be marked on the container.

Progressive: Increasing in scope or severity. Advancing. Going forward. In medicine, a disease that is progressive is going from bad to worse.
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Prostate: A gland within the male reproductive system that is located just below the bladder. Chestnut shaped, the prostate surrounds the beginning of the urethra, the canal that empties the bladder.
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Prostate cancer: An uncontrolled (malignant) growth of cells in the prostate gland which is located at the base of the urinary bladder and is responsible for helping control urination as well as forming part of the semen. Prostate cancer is the second leading cause of death of males in the U.S.

Public health: The approach to medicine that is concerned with the health of the community as a whole. Public health is community health. It has been said that: "Health care is vital to all of us some of the time, but public health is vital to all of us all of the time."
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Quadrant: A quarter. For example, the liver is in the right upper quadrant of the abdomen.
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Random: The process by which an outcome is determined solely by chance, for example, by a coin flip.
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Rebound: Return of the original symptoms when maneuvers or treatment is discontinued.

Receptor: 1. In cell biology, a structure on the surface of a cell (or inside a cell) that selectively receives and binds a specific substance. There are many receptors. There is a receptor for ( insulin ; there is a receptor for low-density lipoproteins ( LDL ); etc. To take an example, the receptor for substance P, a molecule that acts as a messenger for the sensation of pain , is a unique harbor on the cell surface where substance P docks. Without this receptor, substance P cannot dock and cannot deliver its message of pain. Variant forms of nuclear hormone receptors mediate processes such as cholesterol metabolism and fatty acid production. Some hormone receptors are implicated in diseases such as diabetes and certain types of cancer. A receptor called PXR appears to jump-start the body's response to unfamiliar chemicals and may be involved in drug-drug interactions.
2. In neurology, a terminal of a sensory nerve that receives and responds to stimuli.
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Recur: To occur again. To return. Any symptom (such as fatigue), any sign (such as a heart murmur), or any disease can recur.

Recurrence: The return of a sign, symptom or disease after a remission. The reappearance of cancer cells at the same site or in another location is, unfortunately, a familiar form of recurrence.
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Reflux: The term used when liquid backs up into the esophagus from the stomach.

Regress: To return or go back, particularly to return to a pattern of behavior or level of skill characteristic of a younger age. For example, if a three-year-old child begins to regress by losing the ability to control his bowels or speak, that is a cause for medical concern. In reference to a disease, to "regress," means tending to worsen.

Regurgitation: A backward flowing. For example, of food. Or the sloshing of blood back into the heart (or between chambers of the heart) when a heart valve is incompetent and does not close effectively.
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Relapse: The return of signs and symptoms of a disease after a patient has enjoyed a remission . For example, after treatment a patient with cancer of the colon went into remission with no sign or symptom of the tumor, remained in remission for 4 years, but then suffered a relapse and had to be treated once again for colon cancer.
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Resection: Surgical removal of part of an organ.

Residual: Something left behind. With residual disease, the disease has not been eradicated.
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Rule out: A term much used in medicine, meaning to eliminate or exclude something from consideration. The ACB (albumin cobalt binding) test helps rule out a heart attack in the differential diagnosis of severe chest pain.

Section: 1) In anatomy, a slice of tissue. A biopsy obtained by surgery is usually sectioned (sliced), and these sections are inspected under a microscope. 2) In obstetrics, short for Caesarian section. 3) In surgery, the division of tissue during an operation.

Sensation: In medicine and physiology , sensation refers to the registration of an incoming ( afferent ) nerve impulse in that part of the brain called the sensorium , which is capable of such perception. Therefore, the awareness of a stimulus as a result of its perception by sensory receptors. (Sensory is here synonymous with sensation.)
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Sensitivity: 1. In psychology, the quality of being sensitive. As, for example, sensitivity training, training in small groups to develop a sensitive awareness and understanding of oneself and of ones relationships with others. 2. In disease epidemiology, the ability of a system to detect epidemics and other changes in disease occurrence. 3. In screening for a disease, the proportion of persons with the disease who are correctly identified by a screening test. 4. In the definition of a disease, the proportion of persons with the disease who are correctly identified by defined criteria.

Side effects: Problems that occur when treatment goes beyond the desired effect. Or problems that occur in addition to the desired therapeutic effect.
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Skin: The skin is the body's outer covering. It protects us against heat and light, injury, and infection. It regulates body temperature and stores water, fat, and vitamin D. Weighing about 6 pounds, the skin is the body's largest organ. It is made up of two main layers; the outer epidermis and the inner dermis.

Small intestine: The part of the digestive tract that extends from the stomach to the large intestine.

Sodium: The major positive ion (cation) in fluid outside of cells. The chemical notation for sodium is Na⁺. When combined with chloride, the resulting substance is table salt.
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Sore: 1. (adjective) A popular term for painful. I have sore fingers from typing dictionary terms. She has a sore throat . 2. (noun) A nondescript term for nearly any lesion of the skin or mucous membranes. He has a number of sores in his mouth.

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Squamous cells: Flat cells that look like fish scales. The word "squamous" came from the Latin squama meaning "the scale of a fish or serpent."
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Stage: As regards cancer , the extent of a cancer, especially whether the disease has spread from the original site to other parts of the body. See also: Staging .
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Staging: In regard to cancer, the process of doing examinations and tests to learn the extent of the cancer, especially whether it has metastasized (spread) from its original site to other parts of the body.

Stomach: 1. The sac-shaped digestive organ that is located in the upper abdomen, under the ribs. The upper part of the stomach connects to the esophagus, and the lower part leads into the small intestine.
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Stomach cancer : Cancer of the stomach , the main organ that holds food for digestion. Worldwide, stomach cancer is the second most frequent cancer and the second leading cause of death from cancer. It can develop in any part of the stomach and spread to other organs. It is also known as gastric cancer.
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Stress: Forces from the outside world impinging on the individual. Stress is a normal part of life that can help us learn and grow. Conversely, stress can cause us significant problems.
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Stricture: An abnormal narrowing of a body passage, especially a tube or a canal. The stricture may be due, for example, to scar tissue or to a tumor. Stricture refers to both the process of narrowing and the narrowed part itself.
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Sunburn: Sunburn is an inflammation of the skin that develops in response to exposure to ultraviolet (UV) radiation from the sun or from tanning beds and booths that emit UV radiation . Sunburn is manifested by reddened, painful skin that may develop blisters.
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Surgeon: A physician who treats disease, injury, or deformity by operative or manual methods. A medical doctor specialized in the removal of organs, masses and tumors and in doing other procedures using a knife (scalpel). The definition of a "surgeon" has begun to blur in recent years as surgeons have begun to minimize the cutting, employ new technologies that are "minimally invasive," use scopes, etc.
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Surgery: The word "surgery" has multiple meanings. It is the branch of medicine concerned with diseases and conditions which require or are amenable to operative procedures. Surgery is the work done by a surgeon. By analogy, the work of an editor wielding his pen as a scalpel is s form of surgery. A surgery in England (and some other countries) is a physician's or dentist's office.
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Swallowing tube: Descriptive term for the esophagus. See: Esophagus.

Symptom: Any subjective evidence of disease. Anxiety, lower back pain, and fatigue are all symptoms. They are sensations only the patient can perceive. In contrast, a sign is objective evidence of disease. A bloody nose is a sign. It is evident to the patient, doctor, nurse and other observers.

Therapy: The treatment of disease .
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Throat: The throat is the anterior (front) portion of the neck beginning at the back of the mouth , consisting anatomically of the pharynx and larynx . The throat contains the trachea and a portion of the esophagus .
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Tissue: A tissue in medicine is not like a piece of tissue paper. It is a broad term that is applied to any group of cells that perform specific functions. A tissue in medicine need not form a layer. Thus,

• The bone marrow is a tissue;
• Connective tissue consists of cells that make up fibers in the framework supporting other body tissues; and
• Lymphoid tissue is the part of the body's immune system that helps protect it from bacteria and other foreign entities.

Tomography: The process for generating a tomogram , a two-dimensional image of a slice or section through a three-dimensional object. Tomography achieves this remarkable result by simply moving an x-ray source in one direction as the x-ray film is moved in the opposite direction during the exposure to sharpen structures in the focal plane, while structures in other planes appear blurred. The tomogram is the picture; the tomograph is the apparatus; and tomography is the process.
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Tumor: An abnormal mass of tissue. Tumors are a classic sign of inflammation, and can be benign or malignant (cancerous). There are dozens of different types of tumors. Their names usually reflect the kind of tissue they arise in, and may also tell you something about their shape or how they grow. For example, a medulloblastoma is a tumor that arises from embryonic cells (a blastoma) in the inner part of the brain (the medulla). Diagnosis depends on the type and location of the tumor. Tumor marker tests and imaging may be used; some tumors can be seen (for example, tumors on the exterior of the skin) or felt (palpated with the hands).
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Ulcer: An area of tissue erosion, for example, of the skin or lining of the gastrointestinal (GI) tract. Due to the erosion, an ulcer is concave. It is always depressed below the level of the surrounding tissue.
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Ulceration: The process or fact of being eroded away, as by an ulcer.

Ultrasound : High-frequency sound waves. Ultrasound waves can be bounced off of tissues using special devices. The echoes are then converted into a picture called a sonogram. Ultrasound imaging, referred to as ultrasonography, allows physicians and patients to get an inside view of soft tissues and body cavities, without using invasive techniques. Ultrasound is often used to examine a fetus during pregnancy. There is no convincing evidence for any danger from ultrasound during pregnancy.
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Uncertainty: You may be uncertain why "uncertainty" deserves a place in a medical dictionary but some would say that uncertainty is a key element in medicine.
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Voice box:The voice box, or larynx, is the portion of the respiratory (breathing) tract containing the vocal cords which produce sound. It is located between the pharynx and the trachea. The larynx, also called the voice box, is a 2-inch-long, tube-shaped organ in the neck.

Weight loss: Weight loss is a decrease in body weight resulting from either voluntary (diet, exercise) or involuntary (illness) circumstances. Most instances of weight loss arise due to the loss of body fat, but in cases of extreme or severe weight loss, protein and other substances in the body can also be depleted. Examples of involuntary weight loss include the weight loss associated with cancer, malabsorption (such as from chronic diarrheal illnesses ), and chronic inflammation (such as with rheumatoid arthritis).

From the Doctors at MedicineNet.com

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