What formulations of are available barbiturates?
- Amobarbital and pentobarbital are available as injections.
- Butabarbital, phenobarbital, belladonna and phenobarbital, butalbital/aspirin/caffeine, and butalbital/acetaminophen/caffeine are available as tablets.
- Butalbital/acetaminophen/caffeine, butalbital/aspirin/caffeine, and secobarbital are available as capsules.
- Butabarbital, phenobarbital, belladonna and phenobarbital, and butalbital/acetaminophen/caffeine are available as oral liquids.
What about taking barbiturates during pregnancy or while breastfeeding?
FDA has listed amobarbital, phenobarbital, pentobarbital, secobarbital as Pregnancy Category D. This means they should not be used during pregnancy. FDA has listed belladonna and phenobarbital, butabarbital, butalbital/acetaminophen/caffeine, and butalbital/acetaminophen/caffeine as Pregnancy Category C. Pregnancy Category C classification means that there is no evidence of safe and effective use of barbiturates established for pregnant women. Therefore, risk to the infant cannot be ruled out. It is not known whether barbiturates enter breast milk; however, barbiturates should be avoided in nursing mothers to avoid harm to the infant.
REFERENCE: Medscape. Anticonvulsants, Barbiturates.
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