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- What are barbiturates?
- For what conditions are barbiturates prescribed?
- What are examples barbiturates of available in the US?
- What are the side effects of barbiturates?
- What drugs interact with barbiturates?
- What formulations of are available barbiturates?
- What about taking barbiturates during pregnancy or while breastfeeding?
What drugs interact with barbiturates?
Barbiturates should be used with caution with some medications because they accelerate the breakdown of these medications leading to decreased effectiveness. Examples of these medications that interact with barbiturates include:
- atazanavir (Reyataz),
- boceprevir (Victrelis),
- lurasidone (Latuda),
- ranolazine (Ranexa),
- telaprevir (Incivek),
- voriconazole, (Vfend), and
- ritonavir (Norvir).
Concomitant use of barbiturates and other central nervous system depressant medications should be used with caution because concomitant use can lead to excessive sedation, lethargy, and in severe cases coma and death. Examples of these medications that should be used with caution with other central nervous system depressant medications such as:
- alprazolam (Xanax),
- clonazepam (Klonopin),
- diazepam (Valium),
- zolpidem (Ambien), and
- zaleplon (Sonata).
What formulations of are available barbiturates?
- Amobarbital and pentobarbital are available as injections.
- Butabarbital, phenobarbital, belladonna and phenobarbital, butalbital/aspirin/caffeine, and butalbital/acetaminophen/caffeine are available as tablets.
- Butalbital/acetaminophen/caffeine, butalbital/aspirin/caffeine, and secobarbital are available as capsules.
- Butabarbital, phenobarbital, belladonna and phenobarbital, and butalbital/acetaminophen/caffeine are available as oral liquids.
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