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November 25, 2009
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Baclofen Pump Therapy (cont.)

What Is Intrathecal Baclofen?

Baclofen can be taken orally as a pill or delivered directly into an area of the spine called the intrathecal space. The intrathecal space contains the cerebrospinal fluid -- the fluid surrounding the spinal cord and nerve roots. Often MS patients receive intrathecal Baclofen because oral Baclofen causes unpleasant side effects, such as confusion, weakness, and sleepiness. But intrathecal Baclofen delivers the drug right to the target site in the spinal cord. Since the medication does not circulate throughout the body, only tiny doses are required to be effective. Therefore, side effects are minimal.

What Is the Intrathecal Baclofen Pump System?

The intrathecal Baclofen pump system is the way doctors give the drug directly into the spinal fluid. The system consists of a catheter (a small, flexible tube) and a pump. The pump -- a round metal disc, about one inch thick and three inches in diameter -- is surgically placed under the skin of the abdomen near the waistline.

The pump stores and releases prescribed amounts of medicine through the catheter. The pump is refilled by inserting a needle through the skin into a filling port in the center of the pump. With a programmable pump, a tiny motor moves the medication from the pump reservoir through the catheter. Using an external programmer, your treatment team can make adjustments in the dose, rate, and timing of the medication.

People with the pump must return to their doctor's office for pump refills and medication adjustments, typically every 2-3 months. The pump is taken out and replaced at the end of the battery's life span (which is usually 5 to 7 years).

Who Is a Candidate for the Intrathecal Baclofen Pump?

Anyone who has spasticity that is not responsive to oral treatment is a candidate.

If you are considering intrathecal Baclofen therapy, you will generally meet with a treatment team that may include a doctor specialized in rehabilitation (physiatrist), a physical therapist , an occupational therapist , a nurse, and a social worker. All of these professionals work as a team to provide a comprehensive evaluation of your spasticity symptoms and to establish a treatment plan adapted to your personal needs.



Next: What are the advantages of the Baclofen pump system? »

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