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February 10, 2012
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baclofen - injection, Lioresal

GENERIC NAME: BACLOFEN - INJECTION (BAK-loe-fen)

BRAND NAME(S): Lioresal

Warning | Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

WARNING: Serious (rarely fatal) problems may occur if you suddenly stop this medication. Seek immediate medical attention if you experience any of the following signs of a withdrawal reaction: high fever, mental/mood changes (e.g., confusion), worsening of muscle tightness/stiffness, itching, dizziness, numbness/tingling of the hands/feet, unusual change in the amount of urine. Special caution is advised for certain patients who are at greater risk (e.g., patients with spinal cord injuries at T-6 or above, trouble communicating, previous withdrawal reaction with oral or injectable baclofen).

To prevent a withdrawal reaction and to make sure that this drug is not suddenly stopped, always keep your scheduled appointments for refilling the pump. Your doctor will check that the pump is programmed and working properly during these appointments. If you must miss a refill appointment, contact your doctor immediately to reschedule the appointment before you run out of medication. Also learn what your pump alarm sounds like. If you hear the alarm, contact your doctor immediately.

USES: Baclofen is used to treat muscle tightness and cramping (spasms) caused by certain conditions such as spinal cord injury/disease, cerebral palsy, and multiple sclerosis. It works by relaxing the muscles. Decreasing spasms helps reduce pain and stiffness, improves your ability to move around, and lets you do more of your daily activities. Baclofen injection is used in patients who do not respond to or cannot tolerate the side effects of baclofen taken by mouth.

HOW TO USE: This medication is injected only into the space around the spinal cord (intrathecally). This drug is usually given using a drug pump implanted under your skin. A health care professional will usually fill and refill the pump with medication. Dosage is based on your condition and response to treatment.Do not suddenly stop treatment with this drug because serious withdrawal symptoms may occur. See Warning section. To prevent a withdrawal reaction when stopping extended, regular treatment with this drug, gradually reduce the dosage as directed. Consult your doctor or pharmacist for more details.When used for an extended period, this medication may not work as well and may require different dosing. Talk with your doctor if this medication stops working well.Inform your doctor if your condition does not improve or if it worsens.




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