azithromycin, Zithromax, Zmax (cont.)
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
DOSING: Azithromycin (except Zmax) can be taken with or without food, but food reduces stomach upset. Zmax should be taken on an empty stomach 1 hour before or 2 hours after a meal since food reduces its absorption. The adult azithromycin dose is 500-2000 mg in multiple or single doses. For most infections, azithromycin is taken once daily for a relatively short course of treatment (usually five days). The first dose is often a "double dose," twice as much as the remainder of the doses given. For acute bacterial sinusitis, azithromycin way be taken once daily for three days. Zmax usually is given as a single 2 gm dose.
DRUG INTERACTIONS: Azithromycin (except Zmax) should not be taken at the same time as aluminum- or magnesium-based antacids, such as Mylanta or Maalox, because antacids will bind the azithromycin and prevent it from being absorbed from the intestine.
PREGNANCY: There are no adequate studies of azithromycin in pregnant women. Azithromycin should only be used during pregnancy if it is clearly necessary.
NURSING MOTHERS: It is not known if azithromycin is secreted in breast milk.
Medically reviewed by Eni Williams, PharmD
Reference: FDA Prescribing Information
Medically Reviewed by a Doctor on 12/3/2014
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