GENERIC NAME: azelastine hydrochloride and fluticasone propionate
BRAND NAME: Dymista
DRUG CLASS AND MECHANISM: Dymista is a prescription nasal spray used to treat symptoms of seasonal allergic rhinitis (inflammation of the lining of the nose) such as runny nose, stuffy nose, itching, and sneezing. Dymista contains two medicines, azelastine hydrochloride and fluticasone propionate, which are also available individually as nasal sprays. In Dymista, azelastine hydrochloride an antihistamine, and fluticasone propionate, a corticosteroid work in different yet complementary ways.
Azelastine hydrochloride blocks the release and actions of histamine, a chemical responsible for causing many of the symptoms of allergy. Fluticasone propionate is a corticosteroid that reduces inflammation and the body's immune response. When used together, azelastine hydrochloride and fluticasone propionate provide better relief of symptoms than either medicine alone. In clinical trials, Dymista was superior to azelastine nasal spray, fluticasone nasal spray, and placebo in providing symptom relief. Dymista was approved by the FDA in May, 2012.
PRESCRIBED FOR: Dymista is a prescription nasal spray used to treat symptoms of seasonal allergic rhinitis such as runny nose, stuffy nose, itching, and sneezing in patients 12 years of age and older who do not respond adequately to either azelastine hydrochloride or fluticasone propionate alone.
SIDE EFFECTS: The most common side effects of Dymista are changes in taste, nosebleeds, and headache.
Dymista may cause some more serious side effects including:
- sleepiness or drowsiness,
- slow wound healing,
- fungal infections of the nose or throat,
- eye problems such as glaucoma or cataracts,
- increased risk of infections,
- adrenal insufficiency,
- slow or delayed growth in children, and
- nasal problems.
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