DOSING: Azelastine generally is used as 2 sprays in each nostril twice daily.
DRUG INTERACTIONS: Azelastine can promote the sedating effects of other medications that cause sedation. Such drugs include narcotic pain relievers (for example, oxycodone and acetaminophen [ Percocet]), barbiturates, sedatives such as alprazolam (Xanax) or clonazepam (Klonopin), and ethanol.
PREGNANCY: Abnormalities in bones of the skeleton have been noted in animals receiving more than 240 times the human dose of azelastine. There are no adequate studies in pregnant women. Azelastine should be used during pregnancy only if the physician feels that the benefit justifies the potential risk to the fetus.
NURSING MOTHERS: It is not known whether azelastine is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when azelastine is used by a nursing woman.
Medically reviewed by Eni Williams, PharmD
Reference: FDA Prescribing Information
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