azelastine, Astelin

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GENERIC NAME: azelastine


DRUG CLASS AND MECHANISM: Azelastine is an antihistamine, a chemical that blocks the effects of histamine, another chemical that is responsible for some of the symptoms in allergic reactions. Azelastine is chemically different from other antihistamines and is used only as a nasal inhaler for the treatment of symptoms of seasonal allergic rhinitis, such as runny nose, sneezing, and nasal itching in adults and children 12 years of age and older. Azelastine was approved by the FDA in 1996.



PREPARATIONS: Nasal spray: 137 mcg per spray.

STORAGE: The nasal spray should be stored at room temperature, between 15 and 30 C (59-86 F).

PRESCRIBED FOR: Azelastine is used to treat symptoms associated with allergic rhinitis, such as runny nose, sneezing and nasal itching.

DOSING: Azelastine generally is used as 2 sprays in each nostril twice daily.

DRUG INTERACTIONS: Azelastine can promote the sedating effects of other medications that cause sedation. Such drugs include narcotic pain relievers (for example, oxycodone and acetaminophen [ Percocet]), barbiturates, sedatives such as alprazolam (Xanax) or clonazepam (Klonopin), and ethanol.

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