Avian Influenza (Bird Flu) (cont.)

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What is bird flu?

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Bird flu (avian influenza) is a disease caused by an influenza virus that primarily affects birds. In the late 1990s, a new strain of bird flu arose that was remarkable for its ability to cause severe disease and death, especially in domesticated birds such as ducks, chickens, or turkeys. As a result, this strain was called highly pathogenic (meaning very severe and contagious) avian influenza and termed H5N1. A new strain of bird flu has been identified in China. The influenza A virus is termed H7N9 (H7N9 Chinese bird flu). The identification of the virus was reported Mar. 31, 2013; the new strain is different from the H5N1 bird flu virus.

Since the identification of highly pathogenic influenza, infected birds have been found in Asia, Europe, the Middle East, and Africa. Careful control measures, including destroying infected flocks and vaccinating healthy birds, have reduced the number of cases, but the virus continues to exist in poultry flocks in areas of Asia and Africa. Bird flu from the highly pathogenic strain is not found in the United States at this time. Although the H1N1 "swine flu" pandemic strain contained some bird flu genes, it was not the same strain as the original H5N1 bird flu.

The virus spreads through infected birds shedding the virus in their saliva, nasal secretions, and droppings. Healthy birds get infected when they come into contact with contaminated secretions or feces from infected birds. Contact with contaminated surfaces such as cages might also allow the virus to transfer from bird to bird. Symptoms in birds range from mild drops in egg production to failure of multiple major organs and death.

The first human case of illness from highly pathogenic avian influenza (termed HPAI in older literature) was identified in 1997, and 622 cases have been identified since then, with deaths worldwide numbering 371 as of March 2013. Human cases of highly pathogenic bird flu have been largely confined to Southeast Asia and Africa. Mutations often occur in the virus, and it is possible that some mutations could create a more contagious virus that could cause a regional epidemic or a worldwide pandemic of bird flu among humans. Fortunately, the mutations that have occurred to date have not made the virus more contagious, although the concern remains. The identification of a new bird flu strain is worrisome and only careful monitoring will give researchers more clues about this virus strain's ability to infect humans. However, four people in China (two in Shanghai, one in Nanjing, and one in Anhui province) have been identified as being infected with H7N9; two have died. Health officials worldwide are concerned.

Medically Reviewed by a Doctor on 4/5/2013

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