avanafil, Stendra (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

Avanafil and alcohol both lower blood pressure. Therefore, combining avanafil with alcohol may cause excessive drops in blood pressure and cause dizziness, headaches, and increased heart rate.

Avanafil should not be combined with other PDE5 inhibitors used for treating impotence, for example, vardenafil (Levitra) or sildenafil (Viagra, Revatio).

PREGNANCY: Avanafil is not approved for use in women.

NURSING MOTHERS: Avanafil is not approved for women and has not been evaluated in women who are breastfeeding.

SIDE EFFECTS: The most common side effects of avanafil are facial flushing (reddening), headaches, back pain, nasal congestion, dizziness, and upper respiratory tract infections. Diarrhea, nausea, and flu-like symptoms also occur. Avanafil also may cause low blood pressure, blurred vision and changes in color vision, and abnormal ejaculation. Avanafil may cause prolonged erections or priapism (painful erections lasting more than 6 hours). Patients should seek immediate medical help if they experience an erection lasting more than 4 hours. Use of avanafil, especially in patients with pre-existing heart disease, may cause chest pain, heart attacks, death, strokes, palpitations, and increased heart rate. Rare cases of sudden loss of hearing have been reported with phosphodiesterase inhibitors such as avanafil, sometimes associated with ringing in the ears and dizziness. If changes in hearing occur, patients should stop their avanafil and seek immediate medical attention. Phosphodiesterase-5 inhibitors have been associated rarely with non-arteritic anterior ischemic optic neuropathy (NAION), a condition which causes decreased vision and may lead to blindness.

REFERENCE: FDA Prescribing Information


Medically Reviewed by a Doctor on 8/1/2012


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