Melissa Conrad Stöppler, MD, is a U.S. board-certified Anatomic Pathologist with subspecialty training in the fields of Experimental and Molecular Pathology. Dr. Stöppler's educational background includes a BA with Highest Distinction from the University of Virginia and an MD from the University of North Carolina. She completed residency training in Anatomic Pathology at Georgetown University followed by subspecialty fellowship training in molecular diagnostics and experimental pathology.
Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.
Benefits for families: For families, the autopsy has
both tangible and psychological benefits. Uncertainty regarding the cause of an individual's death
can delay payment of insurance benefits. The autopsy can also uncover genetic or
environmental (for example, a bacterium or fungus) causes of disease that could
affect other family members. Psychologically, the autopsy provides closure by
identifying or confirming the cause of death. The autopsy can demonstrate to the
family that the care provided was appropriate, thereby alleviating guilt among
family members and offering reassurance regarding the quality of medical care.
Lastly, the autopsy is a mechanism that enables the family to participate in
medical education and research.
Benefits for the clinician and hospital: The procedure can confirm the
accuracy of the clinical diagnoses and the appropriateness of medical care. The
autopsy findings can be utilized to educate physicians, nurses, residents, and
students, thereby contributing to an improved quality of care.
Benefits to society: Many of the benefits of the autopsy
are experienced by society as a whole. The autopsy aids in the evaluation of new
diagnostic tests, the assessment of new therapeutic interventions (drugs, devices, surgical
techniques), and the investigation of environmental and occupational diseases.
Autopsy data are useful in establishing valid mortality statistics. Data derived
from death certificates in the absence of autopsy data have repeatedly been
shown to be inaccurate. New medical knowledge on existing diseases that is
derived from autopsy-based research is clearly important for everyone.
Remarkably, new diseases continue to emerge which can only be fully investigated
by autopsy.
Dementia is a significant loss of intellectual abilities such as memory capacity, severe enough to interfere with social or occupational functioning. There are different criteria classification schemes for dementias such as cortical, subcortical, progressive, primary, and secondary dementias. Other conditions and medication reactions can also cause dementia. Dementia is diagnosed based on a certain set of criteria. Treatment for dementia is generally focused on the symptoms of the disease.
Brain aneurysm (cerebral aneurysm) is caused by microscopic damage to artery walls, infections of the artery walls, tumors, trauma, drug abuse. Symptoms include headache, numbness of the face, dilated pupils, changes in vision, the "worst headache of your life," or a painful stiff neck. Immediate treatment for a brain aneurysm is crucial for patient survival.
Addison disease is a hormonal (endocrine) disorder involving destruction of the adrenal glands (small glands adjacent to the kidneys). Diseased glands can no longer produce sufficient adrenal hormones (specifically cortisol) necessary for normal daily body functions. Symptoms include weight loss, muscle weakness, fatigue, low blood pressure, and sometimes darkening of the skin. Treatment of Addison disease involves replacing, or substituting, the hormones that the adrenal glands are not making.
Suicide is the process of intentionally ending one's own life. Approximately 1 million people worldwide commit suicide each year, and 10 million to 20 million attempt suicide annually.
A carcinoid tumor is a tumor that develops from enterochromaffin cells. The important characteristic of carcinoid tumors that sets them apart from other gastrointestinal tract tumors, is their potential to cause the carcinoid syndrome. Local symptoms may include abdominal pain, intestinal bleeding, and intestinal obstruction. However, often symptoms of the carcinoid syndrome can be more devastating than the local symptoms. There are many options for the treatment of carcinoid tumors and carcinoid syndrome.
Prolactinoma is an adenoma (benign tumor) of the pituitary gland. Causes of many prolactinomas are unknown. Symptoms in women include changes in menstruation and infertility, decreased libido, or painful intercourse due to vaginal dryness. The most common symptom in men is impotence (erectile dysfunction). Treatment of prolactinomas are medication or surgery.
Trichinosis is a food-borne disease caused by ingesting parasites (roundworms) in undercooked pork or wild-game meat. Symptoms of trichinosis include diarrhea, nausea, muscle aches, itching, fever, chills, and joint pains. Trichinosis usually resolves without treatment, but more severe cases are treated with thiabendazole, albendazole, or mebendazole.
Smoker's lung photo essay is a collection of pictures and microscopic slides of lung disease caused by cigarette smoking. Smoker's lung refers to the diseases and structural abnormalities in the lung caused by cigarette smoking.
Arteriovenous malformation (AVM) is a congenital disorder of blood vessels in the brain, brainstem, or spinal cord that is characterized by a complex, tangled web of abnormal arteries and veins connected by one or more fistulas (abnormal communications). Symptoms of arteriovenous malformations include seizures and headaches. Treatment of arteriovenous malformations include medication or surgery.
Creutzfeldt-Jakob disease (CJD) is a rare, degenerative, invariably fatal brain disorder. CJD generally appears in the later years and runs a rapid course. Symptoms of CJD include failing memory, lack of coordination, visual disturbances, failing memory, blindness, weakness, and eventually coma. There are three major categories of CJD; 1) sporadic CJD, 2) hereditary CJD, and 3) acquired CJD. There is no cure for Creutzfeldt-Jakob disease.
A heart attack is a layperson's term for a sudden blockage of a coronary artery. This photo essay inlcudes graphics, pictures, and illustrations of diseased heart tissue and the mechanisms that lead to coronary artery disease, and possible heart attack.
The cause of sudden infant death syndrome (SIDS) is unknown. The risk of SIDS peaks in infants 2-4 months of age. SIDS is more common among male infants, particularly African American and Native American infants, during the winter months. Putting the baby to sleep on his/her back, avoiding fluffy, loose bedding, using a firm mattress, and avoiding co-sleeping may help to prevent SIDS.