MedicineNet.com

About Us | Privacy Policy | Site Map
February 10, 2012

Autopsy (cont.)

Medical Author:
Medical Editor:

What other special studies may be done as part of the autopsy?

Pictures of findings may be taken for future reference. Special studies may include cultures to identify infectious agents, chemical analysis for the measurement of drug levels or metabolic abnormalities, or genetic studies. Tissue may be frozen for future diagnostic or research purposes. Organs may be preserved and stored in formalin for later examination, sampling for microscopy, presentation at conferences, or archiving for the training of medical students.

What is the autopsy report?

After all studies are completed, a detailed report is prepared that describes the autopsy procedure and microscopic findings, gives a list of medical diagnoses, and a summary of the case. The report emphasizes the relationship or correlation between clinical findings (the doctor's examination, laboratory tests, radiology findings, etc.) and pathologic findings (those made from the autopsy).

Why is the autopsy rate declining?

Beginning in the 1950s, hospital autopsy rates started falling from an average of around 50% of all deaths to 10% in the late 1990s. Currently, the rates are even lower at non-academic hospitals. In 1970, the Joint Commission for Accreditation of Hospitals dropped the requirement that a hospital needed an autopsy rate of 20% to be accredited. To some, this decline represents a crisis in medical education, research, and practice, and deprives decedents' families, physicians, and society of the many benefits of an autopsy.

Multiple factors are believed to contribute to the declining autopsy rate.

Family factors: Certainly the relationship between patients and their doctors has changed dramatically over the past 50 years due to factors such as specialization, managed care, and the disappearance of the "house call." Physicians no longer are "family doctors" and do not have the same rapport with patients and their families as in past years. This change in the basic doctor-patient relationship would seem to make it increasingly difficult to obtain consent for an autopsy, as issues of trust are most certainly involved.

Concerns over disfigurement of the remains or delays in funeral arrangements may prevent a vast majority of families from consenting to an autopsy. In reality, however, the visual examination of the body and the removal of tissues and/or organs for microscopic examination can be completed in a few hours. Furthermore, there are no visible external changes that would preclude an open-casket funeral service.

In the majority of cases and certainly at academic medical centers, there is currently no charge to the family. More recently, though, some institutions have started to charge and private autopsies at the request of family members that are performed outside of the hospital may cost several thousand dollars.

Clinician factors: The perceived and experienced hostility of patients' families towards medical providers may also have an impact on the physician's practice regarding the autopsy. Most physicians are generally uncomfortable requesting an autopsy because it is not an easy or pleasant task. If, in addition, a physician feels that a given family questions the care that their relative was given, the physician may be further dissuaded from requesting an autopsy that might prove that the care that was given was indeed incorrect. During the first half of the century, physicians requested autopsies with the hope of uncovering errors or missed diagnoses that would serve to improve future patient care. This practice may still occur, but sometimes at the price of a lawsuit.

Many individuals in medicine feel that modern technology has made the autopsy outdated or obsolete. With modern imaging studies and laboratory tests, it is thought that the autopsy is unlikely to reveal any conditions that were not detected clinically. The accuracy of the clinical diagnosis has been the subject of numerous research studies. These studies have consistently shown that in 20% to 40% of autopsied patients, there were important, treatable conditions that were detected at autopsy that were not diagnosed clinically. This consistent and significant discrepancy between clinical and pathologic diagnoses is probably the most compelling argument for continued efforts to revive the autopsy as the "gold standard" in evaluating the quality of medical care.

Pathologist factors: Some doctors express dissatisfaction with the quality of an autopsy if the pathologist does not provide answers regarding the case. Unfortunately, an autopsy does not guarantee that the cause of death, for example a heart arrhythmia, will be identified.

Autopsy pathology is a vanishing subspecialty, which, for the most part, has been relegated to a secondary position. At the turn of the century, most of the pathologist's activities revolved around the autopsy. Since that time, laboratory medicine and surgical pathology (examining tissue biopsies from living patients) have become the major activities of practicing pathologists.

In addition, the autopsy is not one of the favorite activities among the majority of pathologists. For many pathologists, an autopsy is an extra burden with no compensation during a busy day.



MedicineNet Doctors

Suggested Reading on Autopsy by Our Doctors

  • Related Diseases & Conditions

    • Dementia
      • Dementia is a significant loss of intellectual abilities such as memory capacity, severe enough to interfere with social or occupational functioning. There are different criteria classification schemes for dementias such as cortical, subcortical, progressive, primary, and secondary dementias. Other conditions and medication reactions can also cause dementia. Dementia is diagnosed based on a certain set of criteria. Treatment for dementia is generally focused on the symptoms of the disease.
    • Aneurysm (Brain)
      • Brain aneurysm (cerebral aneurysm) is caused by microscopic damage to artery walls, infections of the artery walls, tumors, trauma, drug abuse. Symptoms include headache, numbness of the face, dilated pupils, changes in vision, the "worst headache of your life," or a painful stiff neck. Immediate treatment for a brain aneurysm is crucial for patient survival.
    • Addison's Disease
      • Addison disease is a hormonal (endocrine) disorder involving destruction of the adrenal glands (small glands adjacent to the kidneys). Diseased glands can no longer produce sufficient adrenal hormones (specifically cortisol) necessary for normal daily body functions. Symptoms include weight loss, muscle weakness, fatigue, low blood pressure, and sometimes darkening of the skin. Treatment of Addison disease involves replacing, or substituting, the hormones that the adrenal glands are not making.
    • Suicide
      • Suicide is the process of intentionally ending one's own life. Approximately 1 million people worldwide commit suicide each year, and 10 million to 20 million attempt suicide annually.
    • Carcinoid Syndrome and Carcinoid Tumor
      • A carcinoid tumor is a tumor that develops from enterochromaffin cells. The important characteristic of carcinoid tumors that sets them apart from other gastrointestinal tract tumors, is their potential to cause the carcinoid syndrome. Local symptoms may include abdominal pain, intestinal bleeding, and intestinal obstruction. However, often symptoms of the carcinoid syndrome can be more devastating than the local symptoms. There are many options for the treatment of carcinoid tumors and carcinoid syndrome.
    • Prolactinoma (Pituitary Tumor)
      • Prolactinoma is an adenoma (benign tumor) of the pituitary gland. Causes of many prolactinomas are unknown. Symptoms in women include changes in menstruation and infertility, decreased libido, or painful intercourse due to vaginal dryness. The most common symptom in men is impotence (erectile dysfunction). Treatment of prolactinomas are medication or surgery.
    • Trichinosis
      • Trichinosis is a food-borne disease caused by ingesting parasites (roundworms) in undercooked pork or wild-game meat. Symptoms of trichinosis include diarrhea, nausea, muscle aches, itching, fever, chills, and joint pains. Trichinosis usually resolves without treatment, but more severe cases are treated with thiabendazole, albendazole, or mebendazole.
    • Smoker's Lung: Pathology Photo Essay
      • Smoker's lung photo essay is a collection of pictures and microscopic slides of lung disease caused by cigarette smoking. Smoker's lung refers to the diseases and structural abnormalities in the lung caused by cigarette smoking.
    • Arteriovenous Malformation
      • Arteriovenous malformation (AVM) is a congenital disorder of blood vessels in the brain, brainstem, or spinal cord that is characterized by a complex, tangled web of abnormal arteries and veins connected by one or more fistulas (abnormal communications). Symptoms of arteriovenous malformations include seizures and headaches. Treatment of arteriovenous malformations include medication or surgery.
    • Creutzfeldt-Jakob Disease
      • Creutzfeldt-Jakob disease (CJD) is a rare, degenerative, invariably fatal brain disorder. CJD generally appears in the later years and runs a rapid course. Symptoms of CJD include failing memory, lack of coordination, visual disturbances, failing memory, blindness, weakness, and eventually coma. There are three major categories of CJD; 1) sporadic CJD, 2) hereditary CJD, and 3) acquired CJD. There is no cure for Creutzfeldt-Jakob disease.
    • Heart Attack Pathology: Photo Essay
      • A heart attack is a layperson's term for a sudden blockage of a coronary artery. This photo essay inlcudes graphics, pictures, and illustrations of diseased heart tissue and the mechanisms that lead to coronary artery disease, and possible heart attack.
    • Sudden Infant Death Syndrome (SIDS)
      • The cause of sudden infant death syndrome (SIDS) is unknown. The risk of SIDS peaks in infants 2-4 months of age. SIDS is more common among male infants, particularly African American and Native American infants, during the winter months. Putting the baby to sleep on his/her back, avoiding fluffy, loose bedding, using a firm mattress, and avoiding co-sleeping may help to prevent SIDS.
    • Variant Creutzfeldt-Jakob Disease
  • Medications

  • Procedures & Tests

  • Pictures, Images & Illustrations

  • Doctor's & Expert's Views

  • Health News

  • Health Features

Women's Health

Find out what women really need.



Symptom Checker: Your Guide to Symptoms & Signs: Pinpoint Your Pain









Use Pill Finder Find it Now

Pill Identifier on RxList

  • quick,
    easy,
    pill identification

Find a Local Pharmacy

  • including
    24 hour
    pharmacies