HOW TO USE: This medicine comes with a Patient Information Leaflet. Read it carefully. Ask your doctor, nurse, or pharmacist if you have any questions.Take this medication by mouth, usually once or twice a day with or without food or as directed by your doctor. Dosage is based on your medical condition and response to therapy. To decrease side effects such as upset stomach, your doctor may start you at a low dose (once a day) and slowly increase to twice a day. Do not increase your dose or take this medication more often without your doctor's approval. Your condition will not improve any faster, and the risk of serious side effects may be increased. The usual maximum adult dose is 9 milligrams each day.Almost half of all patients have diarrhea or more frequent/loose stools while taking this medication. If this persists or becomes a problem, your doctor may lower the dose or have you temporarily stop the medication. Do not stop or change the dose of your medicine without talking with your doctor.Take this medication regularly in order to get the most benefit from it. To help you remember, take it at the same time(s) each day.If you have been receiving gold injections, you can usually start taking gold by mouth as soon as you stop the injections. If you are changing over from penicillamine, you will usually need to wait 1 month after stopping the penicillamine before starting auranofin. Ask your doctor for more details.It may take 3 to 4 months of therapy before you see the full benefits of this medication.Inform your doctor if your condition persists or worsens.
SIDE EFFECTS: See also How to Use section.Stomach/abdominal cramping may occur, usually within the first several hours after taking this medication. Nausea, loss of appetite, heartburn, and headache may also occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: eye redness/pain, hair loss, numbness/tingling of arms/legs.This medication may cause mouth/lip/throat sores (stomatitis). Tell your doctor if you notice a metallic taste in your mouth. This could be the first sign of stomatitis. Rinsing your mouth with a mild salt solution may provide some relief. Discuss with your doctor.Tell your doctor immediately if any of these rare but very serious side effects occur: signs of low blood count (e.g., fast/pounding heartbeat, pale skin, unusual tiredness), easy bleeding/bruising, black/bloody stools, persistent cough, mucus/pus/blood in watery diarrhea, difficult/painful breathing, dizziness, signs of infection (e.g., fever, persistent sore throat), severe stomach/abdominal pain, unusual tiredness, change in the amount/color of urine, vomit that looks like coffee grounds, yellowing eyes/skin.A very serious allergic reaction to this drug is uncommon. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: itching/swelling (especially of the face/tongue/throat), rash, severe dizziness, trouble breathing.Skin rash is common with this medication and can be serious. Itching is often the first sign of a severe allergic reaction. Therefore, seek immediate medical attention if you develop any rash or itching.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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