attapulgite, Rheaban; Kaopectate Advanced Formula; Parepectolin; Diasorb; Diatrol; Donnagel
Omudhome Ogbru, PharmD
Omudhome Ogbru, PharmD
Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.
Medical and Pharmacy Editor:
GENERIC NAME: attapulgite
BRAND NAME: Rheaban, Kaopectate Advanced Formula, Parepectolin, Diasorb, Diatrol, Donnagel
DRUG CLASS AND MECHANISM: Attapulgite is an oral, nonabsorbed medication that is used in the management of diarrhea. It works by adsorbing (binding) large numbers of bacteria and toxins and reducing the loss of water. Attapulgite reduces the number of bowel movements, improves the consistency of loose or watery stools, and relieves the gastrointestinal cramping that often is associated with diarrhea.
GENERIC AVAILABLE: Yes
PREPARATIONS: Suspension: 600 mg/15ml or 750 mg/ml
STORAGE: Preparations should be stored at room temperature, 15-30 C (59-86 F).
PRESCRIBED FOR: Attapulgite is used for the short-term treatment of diarrhea.
DOSING: Attapulgite is taken after each loose bowel movement.
DRUG INTERACTIONS: Attapulgite can decrease the absorption of benztropine (Cogentin), trihexyphenidyl (Artane), loxapine (Loxitane) and dicyclomine (Bentyl) if taken at the same time. These medications should be taken at least 2 hours earlier or later than attapulgite. Attapulgite and other antidiarrheals can worsen constipation caused by opiate pain relievers such as oxycodone (Percocet), hydrocodone (Vicodin), propoxyphene (Darvon), morphine, and codeine.
PREGNANCY: Attapulgite is safe during pregnancy.
NURSING MOTHERS: Attapulgite is safe to use in nursing mothers.
Reference: FDA Prescribing Information
Last Editorial Review: 7/20/2012
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