atropine ophthalmic (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

SIDE EFFECTS: The most common side effects reported include

  • eye pain,
  • stinging on administration,
  • blurred vision,
  • sensitivity to light,
  • decreased tear production,
  • eyelid swelling, and
  • increased heart rate and blood pressure if the atropine is absorbed from the eye.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Ophthalmic solution: 1%

STORAGE: Atropine ophthalmic solution can be stored in the refrigerator or at room temperature away from heat and light.

DOSING:

  • For inducing mydriasis (pupil dilation) or cycloplegia in adults: Instill 1-2 drops of 1% ophthalmic solution in eye 1 hour before procedure.
  • For the treatment of inflammatory conditions of the eye (iritis or uveitis) in adults: Instill 1-2 drops of 1% solution in eye up to 4 times per day.

DRUG INTERACTIONS:

Use of atropine with monoamine oxidase inhibitors (MAOI) is not recommended due to the risk of causing severely elevated blood pressure (hypertensive crisis). Examples of MAO inhibitors include

  • linezolid (Zyvox),
  • methylene blue,
  • phenelzine (Nardil),
  • procarbazine (Matulane),
  • rasagiline (Azilect),
  • selegiline (Eldepryl, Zelapar, Carbex),
  • tranylcypromine (Parnate) and others.

Patients should ask their doctor or pharmacist before using atropine eye products if they are taking certain drugs such as

Medically Reviewed by a Doctor on 6/16/2015


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