atropine ophthalmic

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

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PREPARATIONS: Ophthalmic solution: 1%

STORAGE: Atropine ophthalmic solution can be stored in the refrigerator or at room temperature away from heat and light.


  • For inducing mydriasis (pupil dilation) or cycloplegia in adults: Instill 1-2 drops of 1% ophthalmic solution in eye 1 hour before procedure.
  • For the treatment of inflammatory conditions of the eye (iritis or uveitis) in adults: Instill 1-2 drops of 1% solution in eye up to 4 times per day.


Use of atropine with monoamine oxidase inhibitors (MAOI) is not recommended due to the risk of causing severely elevated blood pressure (hypertensive crisis). Examples of MAO inhibitors include

Patients should ask their doctor or pharmacist before using atropine eye products if they are taking certain drugs such as

PREGNANCY: There are no adequate and well-controlled studies of atropine sulfate in pregnant women

NURSING MOTHERS: Small amounts of atropine were detected in human milk following administration of injectable atropine. Ophthalmic preparations of atropine are compatible with breastfeeding.

REFERENCE: FDA Prescribing Information.

Medically Reviewed by a Doctor on 6/16/2015
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