atropine ophthalmic (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

SIDE EFFECTS: The most common side effects reported include

  • eye pain,
  • stinging on administration,
  • blurred vision,
  • sensitivity to light,
  • decreased tear production,
  • eyelid swelling, and
  • increased heart rate and blood pressure if the atropine is absorbed from the eye.



PREPARATIONS: Ophthalmic solution: 1%

STORAGE: Atropine ophthalmic solution can be stored in the refrigerator or at room temperature away from heat and light.


  • For inducing mydriasis (pupil dilation) or cycloplegia in adults: Instill 1-2 drops of 1% ophthalmic solution in eye 1 hour before procedure.
  • For the treatment of inflammatory conditions of the eye (iritis or uveitis) in adults: Instill 1-2 drops of 1% solution in eye up to 4 times per day.


Use of atropine with monoamine oxidase inhibitors (MAOI) is not recommended due to the risk of causing severely elevated blood pressure (hypertensive crisis). Examples of MAO inhibitors include

  • linezolid (Zyvox),
  • methylene blue,
  • phenelzine (Nardil),
  • procarbazine (Matulane),
  • rasagiline (Azilect),
  • selegiline (Eldepryl, Zelapar, Carbex),
  • tranylcypromine (Parnate) and others.

Patients should ask their doctor or pharmacist before using atropine eye products if they are taking certain drugs such as

Medically Reviewed by a Doctor on 6/16/2015

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