atovaquone and proguanil (Malarone) oral

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GENERIC NAME: Atovaquone and proguanil hydrochloride

BRAND NAME: Malarone

DRUG CLASS AND MECHANISM: Atovaquone and proguanil is an anti-malarial medication. Atovaquone blocks mitochondrial electron transfer and thereby the production of energy for use by the parasites. Proguanil is metabolized into its active metabolite, cycloguanil, which blocks dihydrofolate reductase and enzymes required for making pyrimidine which is a chemical needed for production of DNA.

PRESCRIBED FOR: Atovaquone and proguanil is used for prevention and treatment of P. Falciparum malaria.

SIDE EFFECTS: Common side effects of atovaquone and proguanil are:

Medically Reviewed by a Doctor on 9/10/2015

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