atorvastatin (cont.)
More often, statins cause abnormalities of liver tests, and,
therefore, periodic measurement of
liver tests in the blood is recommended for
all statins. Abnormal tests usually return to normal even if a statin is
continued, but if the abnormal test value is greater than three times the upper
limit of normal, the statin usually is stopped. Liver tests should be measured
before initiation, at 12 weeks following initiation of therapy and dose changes,
and periodically thereafter.
Inflammation of the muscles caused by statins can lead to serious breakdown
of muscle cells called rhabdomyolysis. Rhabdomyolysis causes the release of
muscle protein (myoglobin) into the blood, and myoglobin can cause
kidney
failure and even death. When used alone, statins cause rhabdomyolysis in less
than one percent of patients. To prevent the development of serious
rhabdomyolysis, patients taking atorvastatin should contact their healthcare
provider immediately if they develop unexplained muscle pain, weakness, or
muscle tenderness.
Last Editorial Review: 4/14/2008
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
- simvastatin, Zocor - Read about the medication simvastatin (Zocor) a cholesterol- lowering drug used to inhibit the production of cholesterol by the liver. Article includes descriptions, uses, drug interactions, and side effects.
- Liver Blood Tests - Learn about liver blood tests used to detect liver damage disease such as fatty liver, cirrhosis, hepatitis, Tylenol liver damage, and more. This includes measuring the aminotransferases enzymes (AST and ALT levels)
- Stroke - Learn about strokes symtoms like sudden numbness or weakness in the face, arms, or legs, confusion, vision problems, problems with walking or coordination, or severe headache.
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