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February 10, 2012

Atopic Dermatitis Glossary of Terms

The following are health and medical definitions of terms that appear in the Atopic Dermatitis article.

Aging: The process of becoming older, a process that is genetically determined and environmentally modulated.
See the entire definition of Aging

Allergen: A substance that is foreign to the body and can cause an allergic reaction in certain people. For examples, pollen, dander, mold.

Allergic contact eczema: Also called allergic contact dermatitis, this is a red, itchy, weepy reaction where the skin has come into contact with a substance that the immune system recognizes as foreign, such as poison ivy or certain preservatives in creams and lotions.

Allergic reaction: The hypersensitive response of the immune system of an allergic individual to a substance.
See the entire definition of Allergic reaction

Allergy: A misguided reaction to foreign substances by the immune system, the body system of defense against foreign invaders, particularly pathogens (the agents of infection). The allergic reaction is misguided in that these foreign substances are usually harmless. The substances that trigger allergy are called allergen. Examples include pollens, dust mite, molds, danders, and certain foods. People prone to allergies are said to be allergic or atopic.
See the entire definition of Allergy

Antibody: An immunoglobulin, a specialized immune protein, produced because of the introduction of an antigen into the body, and which possesses the remarkable ability to combine with the very antigen that triggered its production.
See the entire definition of Antibody

Antihistamines: Drugs that combat the histamine released during an allergic reaction by blocking the action of the histamine on the tissue. Antihistamines do not stop the formation of histamine nor do they stop the conflict between the IgE and antigen. Therefore, antihistamines do not stop the allergic reaction but protect tissues from some of its effects. Antihistamines frequently cause mouth dryness and sleepiness. Newer "non sedating" antihistamines are generally thought to be somewhat less effective. Antihistamine side effects that very occasionally occur include urine retention in males and fast heart rate.

Anxiety: A feeling of apprehension and fear characterized by physical symptoms such as palpitations, sweating, and feelings of stress. Anxiety disorders are serious medical illnesses that affect approximately 19 million American adults. These disorders fill people's lives with overwhelming anxiety and fear. Unlike the relatively mild, brief anxiety caused by a stressful event such as a business presentation or a first date, anxiety disorders are chronic, relentless, and can grow progressively worse if not treated.
See the entire definition of Anxiety

Arms: An appendage in anatomy and in clinical trials. See: Arm.

Asthma: A common disorder in which chronic inflammation of the bronchial tubes (bronchi) makes them swell, narrowing the airways. Asthma involves only the bronchial tubes and does not affect the air sacs (alveoli) or the lung tissue (the parenchyma of the lung) itself.
See the entire definition of Asthma

Atopic: Prone to allergies or characterized by allergy.

Atopic dermatitis: A skin disease characterized by areas of severe itching, redness, scaling, and loss of the surface of the skin (excoriation). When the eruption (rash) has been present for a prolonged time, chronic changes occur due to the constant scratching and rubbing known as lichenification (thickening of the skin with accentuation of the skin lines to form a crisscross pattern).
See the entire definition of Atopic dermatitis

Atopy: The genetic tendency to develop the classic allergic diseases -- atopic dermatitis, allergic rhinitis (hay fever), and asthma. Atopy involves the capacity to produce IgE in response to common environmental proteins such as house dustmite, grass pollen, and food allergens. From the Greek atopos meaning out of place.

Atrophy: Wasting away or diminution. Muscle atrophy is wasting of muscle, decrease in muscle mass.
See the entire definition of Atrophy

Bacteria: Single-celled microorganisms which can exist either as independent (free-living) organisms or as parasites (dependent upon another organism for life).
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Bacterial: Of or pertaining to bacteria. For example, a bacterial lung infection.

Biopsy: The removal of a sample of tissue for purposes of diagnosis. (Many definitions of "biopsy" stipulate that the sample of tissue is removed for examination under a microscope. This may or may not be the case. The diagnosis may be achieved by other means such as by analysis of chromosomes or genes.)
See the entire definition of Biopsy

Blood pressure: The blood pressure is the pressure of the blood within the arteries. It is produced primarily by the contraction of the heart muscle. It's measurement is recorded by two numbers. The first (systolic pressure) is measured after the heart contracts and is highest. The second (diastolic pressure) is measured before the heart contracts and lowest. A blood pressure cuff is used to measure the pressure. Elevation of blood pressure is called "hypertension".

Blood sugar: Blood glucose. See also: High blood sugar; Low blood sugar.

Breastfeeding: Feeding a child human breast milk. According to the American Academy of Pediatrics, human breast milk is preferred for all infants. This includes even premature and sick babies, with rare exceptions. It is the food least likely to cause allergic reactions; it is inexpensive; it is readily available at any hour of the day or night; babies accept the taste readily; and the antibodies in breast milk can help a baby resist infections.
See the entire definition of Breastfeeding

Bumps: The raised area of a bump or bruise results from blood leaking from these injured blood vessels into the tissues as well as from the body's response to the injury. A purplish, flat bruise that occurs when blood leaks out into the top layers of skin is referred to as an ecchymosis.

Cancer: An abnormal growth of cells which tend to proliferate in an uncontrolled way and, in some cases, to metastasize (spread).
See the entire definition of Cancer

Cascade: A sequence of successive activation reactions involving enzymes (enzyme cascade) or hormones (hormone cascade) characterized by a series of amplifications of an initial stimulus. In blood coagulation, for example, each enzyme activates the next until the final product, the fibrin clot, is reached.

Cell: The basic structural and functional unit in people and all living things. Each cell is a small container of chemicals and water wrapped in a membrane.
See the entire definition of Cell

Cheilitis: Inflammation of the lips or of a lip. Cheilitis can also be spelled chilitis.
See the entire definition of Cheilitis

Chin: Medically, the mentum. The lower portion of the face below the lower lip including the prominence of the lower jaw and the line of fusion of the two separate halves of the jawbone (mandible). This line of fusion (called the symphysis menti) encloses a triangular area at tip of the chin (termed the mental protuberance). On each side, below the second premolar tooth, is the mental foramen, an opening for the passage of blood vessels and a nerve that supply the chin.

Chronic: This important term in medicine comes from the Greek chronos, time and means lasting a long time.
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Circulatory: Having to do with the circulation, the movement of fluid in a regular or circuitous course. Although the adjective "circulatory" need not necessarily refer to the circulation of the blood, for all practical purposes today it does. A circulatory problem is taken usually to be a problem with the blood circulation, for example with heart failure.

Clinical trials: Trials to evaluate the effectiveness and safety of medications or medical devices by monitoring their effects on large groups of people.
See the entire definition of Clinical trials

Congestion: An abnormal or excessive accumulation of a body fluid. The term is used broadly in medicine. Examples include nasal congestion (excess mucus and secretions in the air passages of the nose) seen with a common cold and congestion of blood in the lower extremities seen with some types of heart failure.

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Contact dermatitis: A skin condition caused by contact between skin and some substance. Includes irritant contact dermatitis (a rash brought on purely by repeated irritation from a substance such as water causing "dish pan hands") and allergic contact dermatitis (involving a specific sensitivity or allergy to a specific substance such as poison ivy).

Contact eczema: A localized reaction that includes redness, itching, and burning where the skin has come into contact with an allergen (an allergy-causing substance) or with an irritant such as an acid, a cleaning agent or another chemical.

Corticosteroid: Any of the steroid hormones made by the cortex (outer layer) of the adrenal gland. Cortisol is a corticosteroid.

Cortisone: An adrenocorticoid hormone, a naturally occurring hormone made by and secreted by the adrenal cortex, the outer part (the cortex) of the adrenal gland.
See the entire definition of Cortisone

Dander: Tiny scales shed from human or animal skin or hair. Dander floats in the air, settles on surfaces and makes up much household dust. Cat dander is a classic cause of allergic reactions.

Dandruff: A mild skin condition that produces white flakes that may be shed and fall from the hair.
See the entire definition of Dandruff

Depression: An illness that involves the body, mood, and thoughts, that affects the way a person eats and sleeps, the way one feels about oneself, and the way one thinks about things. A depressive disorder is not the same as a passing blue mood. It is not a sign of personal weakness or a condition that can be wished away. People with a depressive disease cannot merely "pull themselves together" and get better. Without treatment, symptoms can last for weeks, months, or years. Appropriate treatment, however, can help most people with depression.
See the entire definition of Depression

Dermatitis: Inflammation of the skin, either due to direct contact with an irritating substance, or to an allergic reaction. Symptoms of dermatitis include redness, itching, and in some cases blistering.
See the entire definition of Dermatitis

Dermatologist: A doctor who specializes in the diagnosis and treatment of skin problems.

Diagnosis: 1 The nature of a disease; the identification of an illness. 2 A conclusion or decision reached by diagnosis. The diagnosis is rabies. 3 The identification of any problem. The diagnosis was a plugged IV.
See the entire definition of Diagnosis

Diarrhea: A familiar phenomenon with unusually frequent or unusually liquid bowel movements, excessive watery evacuations of fecal material. The opposite of constipation. The word "diarrhea" with its odd spelling is a near steal from the Greek "diarrhoia" meaning "a flowing through." Plato and Aristotle may have had diarrhoia while today we have diarrhea. There are myriad infectious and noninfectious causes of diarrhea.
See the entire definition of Diarrhea

Dry skin: Abnormally dry skin. Can be caused by a dry climate, winter weather, deficiency of vitamin A, systemic illness, overexposure to sunlight, or medication. The skin loses moisture. It may crack and peel. Or it may become irritated, inflamed, and itch. Bathing frequently, especially with soaps, can contribute to dry skin.
See the entire definition of Dry skin

Dust mite: A tiny microscopic organism that is the primary cause of allergies related to house dust. The term "dust mite allergy" is a misnomer because it is the excretion of these mites to which people are allergic. Dust mites can therefore trigger allergic reactions even when dead.

Dyshidrotic eczema: Irritation of the skin on the palms of hands and soles of the feet characterized by clear, deep blisters that itch and burn.

Ear: The hearing organ. There are three sections of the ear, according to the anatomy textbooks. They are the outer ear (the part we see along the sides of our head behind the temples), the middle ear, and the inner ear. But in terms of function, the ear has four parts: those three and the brain. Hearing thus involves all parts of the ear as well as the auditory cortex of the brain. The external ear helps concentrate the vibrations of air on the ear drum and make it vibrate. These vibrations are transmitted by a chain of little bones in the middle ear to the inner ear. There they stimulate the fibers of the auditory nerve to transmit impulses to the brain.
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Eczema: A particular type of inflammatory reaction of the skin in which there are typically vesicles (tiny blister-like raised areas) in the first stage followed by erythema (reddening), edema (swelling), papules (bumps), and crusting of the skin followed, finally, by lichenification (thickening) and scaling of the skin. Eczema characteristically causes itching and burning of the skin.
See the entire definition of Eczema

Elidel: Brand name of pimecrolimus.

Epidermal: Pertaining to the epidermis, the outermost layer of the skin.

Epidermis: The upper or outer layer of the two main layers of cells that make up the skin. The epidermis is mostly made up of flat, scale-like cells called squamous cells. Under the squamous cells are round cells called basal cells. The deepest part of the epidermis also contains melanocytes. These cells produce melanin, which gives the skin its color.
See the entire definition of Epidermis

Essential: 1. Something that cannot be done without.
2. Required in the diet, because the body cannot make it. As in an essential amino acid or an essential fatty acid.
3. Idiopathic. As in essential hypertension. "Essential" is a hallowed term meaning "We don't know the cause."

Exacerbate: To make worse. For example, smoking may exacerbate systemic lupus erythematosus.

Family history: The family structure and relationships within the family, including information about diseases in family members.
See the entire definition of Family history

FDA: The Food and Drug Administration, an agency within the U.S. Public Health Service, which is a part of the Department of Health and Human Services.
See the entire definition of FDA

Fever: Although a fever technically is any body temperature above the normal of 98.6 degrees F. (37 degrees C.), in practice a person is usually not considered to have a significant fever until the temperature is above 100.4 degrees F (38 degrees C.).
See the entire definition of Fever

Food and Drug Administration: The FDA, an agency within the U.S. Public Health Service, which is a part of the Department of Health and Human Services.
See the entire definition of Food and Drug Administration

Fungal: Pertaining to a fungus. For example, a fungal skin infection.

Gastrointestinal: Adjective referring collectively to the stomach and small and large intestines.
See the entire definition of Gastrointestinal

Genetic: Having to do with genes and genetic information.

Gooseflesh: A temporary local change in the skin when it becomes rougher due to erection of little muscles, as from cold, fear, or excitement.
See the entire definition of Gooseflesh

Hay fever: A seasonal allergy to airborne particles characterized by itchy eyes, runny nose, nasal congestion, sneezing, itchy throat, and excess mucus.
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Herpes: A family of viruses. Herpes also refers to infection with one of the human herpesviruses, especially herpes simplex types 1 and 2.
See the entire definition of Herpes

High blood pressure: Also known as hypertension, high blood pressure is, by definition, a repeatedly elevated blood pressure exceeding 140 over 90 mmHg -- a systolic pressure above 140 with a diastolic pressure above 90.
See the entire definition of High blood pressure

High blood sugar: An elevated level of the sugar glucose in the blood. Also called hyperglycemia.
See the entire definition of High blood sugar

Hives: A raised, itchy area of skin that is usually a sign of an allergic reaction. It can be rounded or flat-topped but is always elevated above the surrounding skin. It reflects circumscribed dermal edema (local swelling of the skin). The hives are usually well circumscribed but may be coalescent and will blanch with pressure. They typically last less than 4 hours but they may stay for days or weeks. Approximately 20% of the population has experienced a bout of hives.
See the entire definition of Hives

Ichthyosis: Dry, rectangular scales on the skin. Like fish scales. From the Greek "ichthys" meaning fish.
See the entire definition of Ichthyosis

Immune: Protected against infection. The Latin immunis means free, exempt.

Immune system: A complex system that is responsible for distinguishing us from everything foreign to us, and for protecting us against infections and foreign substances. The immune system works to seek and kill invaders.
See the entire definition of Immune system

Immunoglobulin: A protein produced by plasma cells and lymphocytes and characteristic of these types of cells. Immunoglobulins play an essential role in the body's immune system. They attach to foreign substances, such as bacteria, and assist in destroying them. Immunoglobulin is abbreviated Ig. The classes of immunoglobulins are termed immunoglobulin A (IgA), immunoglobulin G (IgG), immunoglobulin M (IgM), immunoglobulin D (IgD) and immunoglobulin E (IgE).

Immunoglobulin E: Abbreviated IgE. A class of immunoglobulins that includes the antibodies elicited by an allergic substance (allergen). A person who has an allergy usually has elevated blood levels of IgE. IgE antibodies attack and engage the invading army of allergens.

Immunosuppressive: 1. Pertaining to immunosuppression, the suppression of the immune system.
2. An agent capable of suppressing the immune response.

Infant: A child up to 2 years (24 months) of age.
See the entire definition of Infant

Infection: The growth of a parasitic organism within the body. (A parasitic organism is one that lives on or in another organism and draws its nourishment therefrom.) A person with an infection has another organism (a "germ") growing within him, drawing its nourishment from the person.
See the entire definition of Infection

Inflammation: A basic way in which the body reacts to infection, irritation or other injury, the key feature being redness, warmth, swelling and pain. Inflammation is now recognized as a type of nonspecific immune response.
See the entire definition of Inflammation

Interferon: A naturally occurring substance that interferes with the ability of viruses to reproduce. Interferon also boosts the immune system.
See the entire definition of Interferon

Irritant contact dermatitis: A rash brought about by constant irritation from a substance. For example, anyone who washes their hands many times a day can develop "dish pan hands." Another example is in young children who lick their lips repeatedly, resulting in an irritant reaction to saliva.

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Itching: An uncomfortable sensation in the skin that feels as if something is crawling on the skin or in the skin, and makes the person want to scratch the affected area.
See the entire definition of Itching

Keratosis: A localized horny overgrowth of the upper layer of skin such as a callus or wart. Among the common forms of keratosis are actinic keratosis and senile keratosis.

Keratosis pilaris: Small rough bumps, generally on the face, upper arms, and thighs.
See the entire definition of Keratosis pilaris

Kidney: One of a pair of organs located in the right and left side of the abdomen which clear "poisons" from the blood, regulate acid concentration and maintain water balance in the body by excreting urine. The kidneys are part of the urinary tract. The urine then passes through connecting tubes called "ureters" into the bladder. The bladder stores the urine until it is released during urination.


See the entire definition of Kidney

Laboratory: A place for doing tests and research procedures and preparing chemicals, etc. Although "laboratory" looks very like the Latin "laboratorium" (a place to labor, a work place), the word "laboratory" came from the Latin "elaborare" (to work out, as a problem, and with great pains), as evidenced by the Old English spelling "elaboratory" designating "a place where learned effort was applied to the solution of scientific problems."

Leg: In popular usage, the leg extends from the top of the thigh down to the foot. However, in medical terminology, the leg refers to the portion of the lower extremity from the knee to the ankle.
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Lichenification: Thick, leathery skin, usually the result of constant scratching and rubbing.
See the entire definition of Lichenification

Lips: Aside from the lips of the mouth, there are two pairs of lips at the entrance to the vagina. They are the labia majora (the larger outside pair) and the labia minora (the smaller inside pair). Together they form part of the vulva (the female external genitalia).

Liver: An organ in the upper abdomen that aids in digestion and removes waste products and worn-out cells from the blood. The liver is the largest solid organ in the body. The liver weighs about three and a half pounds (1.6 kilograms). It measures about 8 inches (20 cm) horizontally (across) and 6.5 inches (17 cm) vertically (down) and is 4.5 inches (12 cm) thick.


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Lubricant: An oily or slippery substance. A vaginal lubricant may be helpful for women who feel pain during intercourse because of vaginal dryness.

Medical history: 1. In clinical medicine, the patient's past and present which may contain clues bearing on their health past, present, and future. The medical history, being an account of all medical events and problems a person has experienced, including psychiatric illness, is especially helpful when a differential diagnosis is needed.
2. The history of medicine.

Microscope: An optical instrument that augments the power of the eye to see small objects. The name microscope was coined by Johannes Faber (1574-1629) who in 1628 borrowed from the Greek to combined micro-, small with skopein, to view. Although the first microscopes were simple microscopes, most (if not all) optical microscopes today are compound microscopes.

Mite: A tiny eight-legged creature belonging to the Order Acarina related to spiders and ticks. Some mites live freely and others as parasites. Mites can attack plants and animals, carry disease, and cause allergies. acaricide.

Moisturize: To dampen; to replenish lost liquid; to add vapor; to humidify. "Moisturize" usually suggests that the thing receiving liquid is made slightly wet, but is not saturated.
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Molluscum contagiosum: A contagious disease of the skin marked by the occurrence of rounded soft tumors of the skin caused by the growth of a virus (one that belongs to the virus family called the Poxviridae).
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Mouth: 1. The upper opening of the digestive tract, beginning with the lips and containing the teeth, gums, and tongue. Foodstuffs are broken down mechanically in the mouth by chewing and saliva is added as a lubricant. Saliva contains amylase, an enzyme that digests starch. 2. Any opening or aperture in the body. The mouth in both senses of the word is also called the os, the Latin word for an opening, or mouth. The o in os is pronounced as in hope. The genitive form of os is oris from which comes the word oral.

Muscle: Muscle is the tissue of the body which primarily functions as a source of power. There are three types of muscle in the body. Muscle which is responsible for moving extremities and external areas of the body is called "skeletal muscle." Heart muscle is called "cardiac muscle." Muscle that is in the walls of arteries and bowel is called "smooth muscle."

Nausea: Nausea, is the urge to vomit. It can be brought by many causes including, systemic illnesses, such as influenza, medications, pain, and inner ear disease. When nausea and/or vomiting are persistent, or when they are accompanied by other severe symptoms such as abdominal pain, jaundice, fever, or bleeding, a physician should be consulted.

Neck: The part of the body joining the head to the shoulders. Also, any narrow or constricted part of a bone or organ that joins its parts as, for example, the neck of the femur bone.

Neurodermatitis: Scaly patches of skin on the head, lower legs, wrists, or forearms caused by a localized itch such as from an insect bite that becomes intensely irritated when scratched.

Nummular eczema: Coin-shaped patches of irritated skin-most common on the arms, back, buttocks, and lower legs that may be crusted, scaling, and extremely itchy.
See the entire definition of Nummular eczema

Ointment: A medication preparation that is applied topically (onto the skin). An ointment has an oil base whereas a cream is water-soluble. (The word ointment comes from the Latin ungere meaning anoint with oil).

Onset: In medicine, the first appearance of the signs or symptoms of an illness as, for example, the onset of rheumatoid arthritis. There is always an onset to a disease but never to the return to good health. The default setting is good health.
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Papules: Small solid rounded bumps rising from the skin that are each usually less than 1 centimeter in diameter (less than 3/8 inch across).
See the entire definition of Papules

Pediatrics: "Pediatrics is concerned with the health of infants, children and adolescents, their growth and development, and their opportunity to achieve full potential as adults." (Richard E.Behrman in Nelson's Textbook of Pediatrics)
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Phototherapy: Treatment with light. For example, a newborn with jaundice may be "put under the lights."

Pigmentation: The coloring of the skin, hair, mucous membranes, and retina of the eye.
See the entire definition of Pigmentation

Pimecrolimus: A chemical used to treat atopic dermatitis (eczema). Pimecrolimus prevents the activation of T cells by blocking the effects of chemicals called cytokines that stimulate T-cells. Pimecrolimus also reduces the ability of mast cells to release chemicals that promote inflammation. Brand name: Elidel. For more information, see: Pimecrolimus.

Poison: Any substance that can cause severe distress or death if ingested, breathed in, or absorbed through the skin. Many substances that normally cause no problems, including water and most vitamins, can be poisonous if taken in too large of a quantity. Poison treatment depends on the substance: if there are treatment instructions on the substance's container and you are sure it contained no other item, follow those directions immediately. Always contact your nearest Poison Control Center if you are concerned about possible poison ingestion.

Poison ivy: Skin inflammation resulting from contact with oils from the poison ivy vine. Chemicals produced by this vine cause an immune reaction, producing redness, itching, and blistering of the skin.
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Pollen: Small, light, dry protein particles from trees, grasses, flowers, and weeds that may be spread by the wind. Pollen particles are usually the male sex cells of the plant, and are smaller than the tip of a pin. Pollen is a potent stimulator of allergic responses. It lodges in the mucus membranes that line the nose and in other parts of the respiratory tract, causing irritation and histamine reactions.

Pregnancy: The state of carrying a developing embryo or fetus within the female body. This condition can be indicated by positive results on an over-the-counter urine test, and confirmed through a blood test, ultrasound, detection of fetal heartbeat, or an X-ray. Pregnancy lasts for about nine months, measured from the date of the woman's last menstrual period (LMP). It is conventionally divided into three trimesters, each roughly three months long.
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Prevalence: The proportion of individuals in a population having a disease. Prevalence is a statistical concept referring to the number of cases of a disease that are present in a particular population at a given time.

Psoralen: Any of a number of drugs and other substances containing chemicals that react with ultraviolet (UV) light to cause darkening of the skin.

Puberty: A complex biologic and psychologic process involving sexual development, accelerated growth, and adrenal maturation heralded by the secretion of gonadotropin releasing hormone (GnRH) from a part of the brain called the hypothalamus. This event is the first known step in the reproductive cascade. It initiates the pulsatile release of gonadotropins, gonadal secretion of sex steroids, pubertal development, and gametogenesis (the production of sperm and ova).
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Quality of life: An important consideration in medical care, quality of life refers to the patient's ability to enjoy normal life activities. Some medical treatments can seriously impair quality of life without providing appreciable benefit, while others greatly enhance quality of life.

Rash: Breaking out (eruption) of the skin. Medically, a rash is referred to as an exanthem.

Recurrence: The return of a sign, symptom or disease after a remission. The reappearance of cancer cells at the same site or in another location is, unfortunately, a familiar form of recurrence.
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Recurrent: Back again. A recurrent fever is a fever that has returned after an intermission: a recrudescent fever.

Regimen: With the accent on the first syllable (reg as in Reggie Jackson), a regimen is a plan, a regulated course such as a diet, exercise or treatment, designed to give a good result. A low-salt diet is a regimen.

Relapse: The return of signs and symptoms of a disease after a patient has enjoyed a remission. For example, after treatment a patient with cancer of the colon went into remission with no sign or symptom of the tumor, remained in remission for 4 years, but then suffered a relapse and had to be treated once again for colon cancer.
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Remission: Disappearance of the signs and symptoms of cancer or other disease. When this happens, the disease is said to be "in remission." A remission can be temporary or permanent.

Respiratory: Having to do with respiration, the exchange of oxygen and carbon dioxide. From the Latin re- (again) + spirare (to breathe) = to breathe again.

Rule out: A term much used in medicine, meaning to eliminate or exclude something from consideration. The ACB (albumin cobalt binding) test helps rule out a heart attack in the differential diagnosis of severe chest pain.

Saliva: a watery secretion in the mouth produced by the salivary glands that aids in the digestion of food. Saliva also serves to moisten and cleanse the mouth, including the tongue and teeth, and contains substances that can play a role in the prevention of infection. Saliva aids digestion by moistening food and contains enzymes that begin the digestion process. Also known as spit.

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Scaling: Abnormal shedding or accumulation of an upper layer of skin (the stratum corneum).

Seborrhea: A chronic inflammatory disease of the skin characterized by the accumulation of scales of greasy skin. There may be yellow crusted patches that are itchy. Seborrhea often affects the scalp. Other sites include the face, ears, eyebrows and eyelids, umbilicus, and genitalia, Seborrhea of the scalp is commonly known as dandruff.
See the entire definition of Seborrhea

Seborrheic dermatitis: A medical name for what is popularly called seborrhea.

Seborrheic eczema: Yellowish, oily, scaly patches of skin on the scalp, face, and occasionally other parts of the body.

Sensitivity: 1. In psychology, the quality of being sensitive. As, for example, sensitivity training, training in small groups to develop a sensitive awareness and understanding of oneself and of ones relationships with others. 2. In disease epidemiology, the ability of a system to detect epidemics and other changes in disease occurrence. 3. In screening for a disease, the proportion of persons with the disease who are correctly identified by a screening test. 4. In the definition of a disease, the proportion of persons with the disease who are correctly identified by defined criteria.

Skin biopsy: Removal of a piece of skin for the purpose of further examination in the laboratory using a microscope.


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Sleep: The body's rest cycle.
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Staph: Very commonly used shortened form of Staphylococcus, a very common and important group of bacteria. See Staphylococcus.

Staphylococcus: A group of bacteria that cause a multitude of diseases. Under a microscope, Staphylococcus bacteria are round and bunched together. They can cause illness directly by infection, or indirectly through products they make, such as the toxins responsible for food poisoning and toxic shock syndrome. The best known member of the Staphylococcus family is Staphylococcus aureus. Staphylococcus are the main culprit in hospital-acquired infections, and cause thousands of deaths every year.

Stasis: Stasis refers to a stoppage or slowdown in the flow of blood (or other body fluid such as lymph).
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Stasis dermatitis: A skin irritation on the lower legs generally related to circulatory problems.
See the entire definition of Stasis dermatitis

Stress: Forces from the outside world impinging on the individual. Stress is a normal part of life that can help us learn and grow. Conversely, stress can cause us significant problems.
See the entire definition of Stress

Substance: 1. Material with particular features, as a pressor substance.
2. The material that makes up an organ or structure. Also known in medicine as the substantia.
3. A psychoactive drug as, for example, in substance abuse.

Superficial: In anatomy, on the surface or shallow. As opposed to deep. The skin is superficial to the muscles. The cornea is on the superficial surface of the eye.
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Sweating: The act of secreting fluid from the skin by the sweat (sudoriferous) glands. These are small tubular glands situated within and under the skin (in the subcutaneous tissue). They discharge by tiny openings in the surface of the skin.
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Symptom: Any subjective evidence of disease. Anxiety, lower back pain, and fatigue are all symptoms. They are sensations only the patient can perceive. In contrast, a sign is objective evidence of disease. A bloody nose is a sign. It is evident to the patient, doctor, nurse and other observers.

Systemic: Affecting the entire body. A systemic disease such as diabetes can affect the whole body. Systemic chemotherapy employs drugs that travel through the bloodstream and reach and affect cells all over the body.

Tacrolimus: A drug that suppresses the immune system and prevents transplant rejection. The drug acts by inhibiting the activation of T cells.
See the entire definition of Tacrolimus

Therapy: The treatment of disease.
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Topical: Pertaining to a particular surface area. A topical agent is applied to a certain area of the skin and is intended to affect only the area to which it is applied. Whether its effects are indeed limited to that area depends upon whether the agent stays where it is put or is absorbed into the blood stream.

Trait: In genetics, a trait refers to any genetically determined characteristic. In technical terms, a genetic trait is amenable to segregation analysis rather than quantitative analysis.
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Trigger: Something that either sets off a disease in people who are genetically predisposed to developing the disease, or that causes a certain symptom to occur in a person who has a disease. For example, sunlight can trigger rashes in people with lupus.

Ultraviolet A: One of the three types of invisible light rays (together with ultraviolet B and ultraviolet C) given off by the sun.
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Urticaria: Another name for the hives. Raised, itchy areas of skin that are usually a sign of an allergic reaction. Hives can be rounded or flat-topped but are always elevated above the surrounding skin. They reflect circumscribed dermal edema (local swelling of the skin). The hives are usually well circumscribed but may be coalescent and will blanch with pressure.
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Varicose veins: See: Varicose vein.

Viral: Of or pertaining to a virus. For example, "My daughter has a viral rash."

Viral infection: Infection caused by the presence of a virus in the body. Depending on the virus and the person's state of health, various viruses can infect almost any type of body tissue, from the brain to the skin. Viral infections cannot be treated with antibiotics; in fact, in some cases the use of antibiotics makes the infection worse. The vast majority of human viral infections can be effectively fought by the body's own immune system, with a little help in the form of proper diet, hydration, and rest. As for the rest, treatment depends on the type and location of the virus, and may include anti-viral or other drugs.

Virus: A microorganism smaller than a bacteria, which cannot grow or reproduce apart from a living cell. A virus invades living cells and uses their chemical machinery to keep itself alive and to replicate itself. It may reproduce with fidelity or with errors (mutations)-this ability to mutate is responsible for the ability of some viruses to change slightly in each infected person, making treatment more difficult.
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Wheezing: A whistling noise in the chest during breathing when the airways are narrowed or compressed.

White blood cell: One of the cells the body makes to help fight infections. There are several types of white blood cells (leukocytes). The two most common types are the lymphocytes and neutrophils (also called polymorphonuclear leukocytes, PMNs, or "polys").
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  • Related Diseases & Conditions

    • Rash
      • The word "rash" means an outbreak of red bumps on the body. The way people use this term, "a rash" can refer to many different skin conditions. The most common of these are scaly patches of skin and red, itchy bumps or patches all over the place.
    • Keratosis Pilaris
      • Keratosis pilaris (KP) is a common skin disorder in which small white or red bumps appear around hair follicles on the upper arms, thighs, buttocks, and cheeks. The cause of KP is unknown. There is no cure for keratosis pilaris, and the condition may resolve on its own. Gentle exfoliation, professional manual extraction, chemical peels, and microdermabrasion, along with topical products, are the best treatments for this condition.
    • Swimmer's Ear
      • Swimmer's ear (external otitis) is an infection of the skin that covers the outer ear canal. Causes of swimmer's ear include excessive water exposure that leads to trapped bacteria in the ear canal. Symptoms include a feeling of fullness in the ear, itching, and ear pain. Chronic swimmer's ear may be caused by eczema, seborrhea, fungus, chronic irritation, and other conditions. Common treatment includes antibiotic ear drops.
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Atopic Dermatitis

What is "swimmer's ear" or acute external otitis?

External otitis or "swimmer's ear" is an infection of the skin covering the outer ear and ear canal. Acute external otitis is commonly a bacterial infection caused by streptococcus, staphylococcus, or pseudomonas types of bacteria. The swimmer's ear infection is usually caused by excessive water exposure. When water collects in the ear canal (frequently trapped by wax), the skin will become soggy and serve as an inviting culture media for bacteria. Cuts or abrasions in the lining of the ear canal (for example, from cotton swab injury) can also predispose to bacterial infection of the ear canal.

What are the symptoms of swimmer's ear?

The first symptom of infection is that the ear will feel full, and it may itch. Next, the ear canal will swell and ear drainage will follow. At this stage the ear will be very painful, especially with movement of the outside portion of the e...

Read the Swimmer's Ear article »




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