- Strattera is taken once or twice daily. It may be taken with or without food. The capsules should never be broken and sprinkled on food. They must be taken whole.
- The recommended starting dose for and children weighing more than 70 kg is 40 mg once daily. The dose is increased after 3 days to 80 mg PO once daily or divided and given every 12 hours. The dose may be increased up to 100 mg daily to achieve the optimal response.
- Children older than 6 years and weighing 70 kg or less should receive 0.5 mg/kg once daily. The dose may be increased after 3 days to 1.2 mg/kg once daily or divided every 12 hours. The maximum daily dose should not to exceed 1.4 mg/kg or 100 mg, whichever is less.
- Strattera should not be taken with a monoamine oxidase inhibitor (MAOI) or within 14 days of stopping an MAOI, for example, phenelzine sulfate (Nardil) and tranylcypromine sulfate (Parnate).
- Fluoxetine (Prozac), paroxetine (Paxil), quinidine, and other medications can block the enzyme in the liver that eliminates Strattera from the body. This can increase the amount of Strattera in the blood and possibly increase the risk of side effects.
PREGNANCY AND BREASTFEEDING SAFETY:
- In some animal studies (rabbits and rats), very high doses of Strattera (6- to 23-fold higher than those that would be used in humans) were associated with lower birth weight and lower fetal survival. No adequate studies have been done in pregnant women. Therefore, before prescribing Strattera to pregnant women, physicians must weight the potential benefits against the potential and unknown risks.
- Strattera is excreted in the breast milk of animals. Although not similarly studied in humans, it is likely that Strattera is excreted in human breast milk as well. The benefits and potential risks of Strattera therefore must be weighed before it is prescribed to nursing mothers.
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