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atazanavir - oral, Reyataz (cont.)

DRUG INTERACTIONS: See also How to Use section.Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor's approval.Atazanavir interacts with many medications. One product that may interact with this drug is: indinavir.Other medications can affect the removal of atazanavir from your body, which may affect how atazanavir works. Examples include boceprevir, carbamazepine, etravirine, phenobarbital, phenytoin, nevirapine, rifamycins (such as rifampin), St. John's wort, voriconazole, among others.Atazanavir can slow down the removal of other medications from your body, which may affect how they work. Examples of affected drugs include some alpha blockers (such as alfuzosin), certain benzodiazepines (midazolam, triazolam), cisapride, ergot alkaloids (such as dihydroergotamine, ergotamine), fluticasone, irinotecan, lurasidone, pimozide, drugs to treat erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, vardenafil), certain "statin" cholesterol drugs (lovastatin, simvastatin), salmeterol, among others.Prescription and nonprescription drugs to treat heartburn, indigestion, or ulcers (including H2 blockers such as famotidine, proton pump inhibitors such as lansoprazole/omeprazole) reduce stomach acid and decrease the absorption of atazanavir. This may prevent atazanavir from working well. Ask your doctor or pharmacist how to use these medications safely.This medication may decrease the effectiveness of hormonal birth control such as pills, patch, or ring. This could cause pregnancy. Talk to your doctor about additional or alternative reliable forms of birth control, and always use an effective barrier method (latex or polyurethane condoms/dental dams) during all sexual activity to decrease the risk of spreading HIV to others. Tell your doctor if you have any new spotting or breakthrough bleeding, because these may be signs that your hormonal birth control is not working well.



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