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February 10, 2012

Asthma Complexities (cont.)

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Masqueraders of asthma

"All that wheezes is not asthma." Other medical conditions can mimic asthma and make the correct diagnosis of asthma more difficult.

Cardiac asthma

Cardiac asthma usually occurs in elderly people who have wheezing and shortness of breath that are due to heart failure. When the heart is too weak to pump blood effectively, fluid will accumulate in the lungs. Fluid in the lungs causes shortness of breath and wheezing. A chest X-ray can be helpful in diagnosing heart failure by demonstrating an enlarged heart (usually a sign of heart failure) along with fluid in the tissues of the lung. Treatment of heart failure involves using diuretics (water pills) to rid the lungs of excess fluid and medications to help the heart muscle pump more effectively. When the heart failure has been adequately controlled, the wheezing will cease. Some people may suffer from asthma and heart failure simultaneously. These patients require treatment for both conditions.

Other bronchial conditions

Acute bronchitis. Acute bronchitis is an infection, usually viral or bacterial, of the bronchi, the larger airways or breathing tubes. The symptoms of acute bronchitis include fever, cough, yellow or green sputum, and, sometimes, wheezing. This combination of coughing and wheezing is sometimes referred to as "asthmatic bronchitis" or post-viral bronchial hyperreactivity of the airways. Acute bronchitis is generally treated with antibiotics and/or antiinflammatory medications such as corticosteroids. The coughing and wheezing usually subside within a few weeks. Some patients with asthma can produce green mucus that may not reflect an ongoing infection but the consequence of airway inflammation or allergic response.

Chronic bronchitis. Chronic bronchitis usually is defined as a daily cough with production of sputum for three months for two years in a row. The most common cause of chronic bronchitis is cigarette smoking. With chronic bronchitis, there is longstanding inflammation and swelling of the inner lining of the airways, and the inflammation and swelling cause narrowing of the airways. The inflammation also stimulates production of mucous within the airways that becomes the sputum produced by coughing. Infections of the airways with viruses or bacteria are common among individuals with chronic bronchitis. Infections further aggravate the inflammation and narrowing of the airways, worsening the symptoms of shortness of breath, coughing, and wheezing. Treatments include antibiotics, quitting cigarette smoking, bronchodilators to expand the airways, and corticosteroids to reduce the inflammation.

Emphysema. Emphysema is a disease where there is permanent destruction of the walls of the air sacs (alveoli) and the small airways (bronchioles). The destruction of the alveolar walls reduces the elasticity of the lung. Loss of elasticity leads to the collapse of the bronchioles, obstructing airflow out of the alveoli. Air becomes permanently "trapped" in the alveoli. Air trapped in the alveoli cannot be exchanged for room air, and this reduces the ability of the lung to get rid of carbon dioxide and take in oxygen. Emphysema is most often caused by years of cigarette smoking; however, a genetic disease, alpha-1 antitrypsin deficiency, also causes emphysema.

The combination of chronic bronchitis and emphysema is called chronic obstructive pulmonary disease (COPD). The major symptom of emphysema is shortness of breath. Patients with emphysema also may wheeze if they also suffer from chronic bronchitis and/or asthma. Treatment of these latter patients begins with smoking cessation and the use of inhalers to deliver bronchodilators and corticosteroids to the lungs. Antibiotics, oxygen, and surgery in the advanced stages of these diseases also can be helpful.

Bronchiectasis. Bronchiectasis is a chronic condition in which the bronchial tubes (larger airways) are damaged by repeated bronchial infections. The major symptom of bronchiectasis is a persistent cough with thick and usually green mucus. Bronchiectasis is treated with bronchodilators, antibiotics, and corticosteroids when flare-ups occur.

Cystic fibrosis is an inherited condition in which the affected patients can produce thick mucus that plugs the bronchial tubes. The plugging of the bronchial tubes causes repeated bouts of bronchitis and pneumonia, leading to the development of bronchiectasis.

Localized bronchial obstruction. Wheezing and coughing can be symptoms of a localized obstruction of the airways (the bronchial tubes or trachea). The wheezing represents the sound of air rushing around the blockage, and the coughing is the body's effort to clear the blockage. The most common causes of localized airway obstruction are foreign bodies such as accidentally inhaled peanuts, bronchial tumors, and the narrowing of the trachea that occurs after a tracheostomy. The wheezing and coughing due to a localized obstruction will not respond to medications for asthma. The treatment is to relieve the obstruction.



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    • Sinus Infection
      • Sinus infection (sinusitis) signs and symptoms include headache, fever, and facial tenderness, pressure, or pain. Treatments of sinus infections are generally with antibiotics and at times, home remedies.
    • Chronic Obstructive Pulmonary Disease
      • COPD (chronic obstructive pulmonary disease) is a disorder that persistently obstructs bronchial airflow. COPD mainly involves three related conditions, chronic bronchitis, chronic asthma, and emphysema. Symptoms of COPD include chronic cough, shortness of breath, frequent respiratory infections, wheezing, morning headaches, and pulmonary hypertension. Treatment of COPD is focused on the related condition(s).
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      • Asthma is a common disorder in which chronic inflammation of the bronchial tubes (bronchi) makes them swell, narrowing the airways. Signs and symptoms include shortness of breath, chest tightness, cough and wheezing.
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      • Emphysema is a progressive disease of the lungs. The primary cause of emphysema is smoking. Alpha 1-antitrypsin deficiency is a rare disorder that has a genetic predisposition to emphysema. Aging, IV drug use, immune deficiencies, and connect tissue illnesses are also risk factors for emphysema. Emphysema is a subtype of COPD (chronic obstructive pulmonary disease, COLD). Symptoms include shortness of breath and wheezing. Management of symptoms may be achieved with medications, quitting smoking, pulmonary rehabilitation, or surgery.
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      • Exercise-induced asthma is asthma triggered by vigorous exercise. Symptoms include coughing, shortness of breath, chest tightness, wheezing, and fatigue while exercising. Preventing exercise-induced asthma attacks involves using inhaled medicines before exercising, performing warm-up exercises and cooling down afterward, avoiding exercising outdoors when pollen counts are high, restricting exercise when you have a viral infection, and wearing a mask over your nose and mouth when exercising in cold weather.
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