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ASTEMIZOLE-ORAL, Hismanal (cont.)

DRUG INTERACTIONS: Tell your doctor of any over-the-counter or prescription medication you may take including sleeping pills, sedatives, tranquilizers, quinine, muscle relaxants, medication for depression (e.g., "SSRI" such as fluoxetine, or nefazodone and protease inhibitors (e.g., indinavir, nelfinavir, saquinavir). Tell your doctor if you have taken any MAO inhibitors (e.g., furazolidone, phenelzine, selegiline, tranylcypromine), within the last two weeks. Inform your doctor if you are taking erythromycin or related drugs (e.g., clarithromycin, troleandomycin) or azole antifungal drugs (e.g., ketoconazole, itraconazole), mibefradil, narcotic pain relievers, anti-seizure medicines, or zileuton. Report other drugs which affect the heart rhythm (QTc prolongation), such as: dofetilide, pimozide, quinidine, sotalol, procainamide, sparfloxacin, "water pills" (diuretics such as furosemide or hydrochlorothiazide). Ask your doctor or pharmacist for more details. Do not eat grapefruit or drink grapefruit juice unless your doctor instructs you otherwise. Do not take this drug for several days before allergy testing as test results can be affected. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include dizziness, irregular or fast heartbeat, fainting, loss of consciousness, and seizures.



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