- A Visual Guide to Heart Disease
- Medical Illustrations of the Heart Image Collection
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- What is aspirin?
- What is aspirin therapy?
- What are the side effects of aspirin?
- What are the latest recommendations on the use of aspirin in the primary prevention of heart (cardiovascular) disease?
- What dosage of aspirin should I take to prevent and treat heart attacks and strokes?
- How effective is aspirin for preventing heart attacks among healthy people?
- Who should take aspirin to prevent and treat heart attacks and strokes?
- Who should not take aspirin to prevent heart attacks and strokes?
- When is aspirin used for preventing and treating heart attacks and strokes?
- Aspirin for treatment of heart attacks
- Aspirin for treatment of exertional and unstable angina
- Aspirin for treatment of ischemic strokes
- What is aspirin allergy?
- What drugs might interact with aspirin?
- What can be done to reduce the risk of ulcers from long-term aspirin use?
- What are the limitations of aspirin treatment?
- What is aspirin resistance?
- What is in the future for the research on aspirin resistance?
What is aspirin allergy?
Allergy to aspirin is a rare condition in which a patient can develop swelling of tissues, spasm of the airways (bronchospasm) that causes difficulty breathing, and even anaphylaxis, a life-threatening condition. Clearly, patients with a history of allergy to aspirin should not take aspirin. Since aspirin is related chemically to the other NSAIDs, patients who are allergic to the other NSAIDs, such as ibuprofen (Motrin) and naproxen (Aleve), also should not take aspirin.
What drugs might interact with aspirin?
Aspirin may interact with other medications and cause undesirable side effects. For example:
- Aspirin, when taken together with an anti-coagulant such as warfarin (Coumadin) or enoxaparin (Lovenox), can greatly impair the body's ability to form blood clots, resulting in excessive bleeding spontaneously, from ulcers, or related to a procedure. Therefore, patients on such combinations must be closely monitored by a doctor.
- Aspirin can raise levels of uric acid in the blood and may need to be avoided in patients with increased uric acid levels or gout.
- Aspirin can increase the effect of medications used for lowering blood sugar levels in patients with diabetes, resulting in abnormally low blood sugar levels (hypoglycemia). Blood sugar levels may need to be more closely monitored.
- Certain NSAIDs, particularly ibuprofen (Motrin, Advil), if taken just before aspirin or in multiples doses each day, can reduce the anti-platelet effects of aspirin and theoretically render aspirin less effective in preventing heart attacks and ischemic strokes. The ibuprofen molecule is believed to adhere to the COX-1 enzyme, thus keeping aspirin from reaching the enzyme.
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