Aseptic Necrosis

Leprosy »

What is leprosy?

Leprosy is a disease caused by the bacteria Mycobacterium leprae that causes damage to the skin and the peripheral nervous system. The disease develops slowly (from six months to 40 years!) and results in skin lesions and deformities, most often affecting the cooler places on the body (for example, eyes, nose, earlobes, hands, feet, and testicles). The skin lesions and deformities can be very disfiguring and are the reason that infected individuals were considered outcasts in many cultures. Although human-to-human transmission is the primary source of infection, three other species can carry and (rarely) transfer M. leprae to humans; chimpanzees, mangabey monkeys, and nine-banded armadillos. The disease is termed a chronic granulomatous disease because it produces inflammatory nodules (granulomas) in the skin and nerves over time.