MedicineNet.com
About Us | Privacy Policy | Site Map
November 8, 2009
MedicineNet home Picture Slideshows Diseases and conditions Symptoms and signs Procedures and tests Medications Health and Living Health news and views MedTerms medical dictionary
Font Size
A
A
A

Artificial Sweeteners (cont.)

Saccharin: What is the positive side?

Saccharin has been around for over 100 years and claims to be the best researched sweetener. Saccharin is also known as Sweet and Low, Sweet Twin, Sweet'N Low, and Necta Sweet. It does not contain any calories, does not raise blood sugar levels and is 200 to 700 times sweeter than sucrose (table sugar).

Out of the five FDA approved nonnutritive sweeteners, saccharin is often chosen to be the safest one. The FDA's guidelines on the use of saccharin for beverages are not to exceed 12 mg/fluid ounce, and in processed food, the amount is not to exceed 30 mg per serving. The Acceptable Daily Intake (ADI) for saccharin is 5 mg/kg of body weight. To determine your ADI, divide your weight in pounds by 2.2 and then multiply it by 5. For example, if you weighed 180 lbs., your weight in kg would be 82 (180 divided by 2.2) and your ADI for saccharin would be 410 mg (5 x 82). Saccharin is used in tabletop sweeteners, baked goods, jams, chewing gum, canned fruit, candy, dessert toppings, and salad dressings. It also is useful in cosmetic products, vitamins, and pharmaceuticals.

There was a great deal of controversy surrounding the safety of saccharin back in the '70s. In 1977, research showed bladder tumors in male rats with the ingestion of saccharin. The FDA proposed a ban on saccharin based on the Delaney Clause of the Federal Food, Drug, and Cosmetic Act, enacted in 1958. This clause prohibits the addition to the human food supply of any chemical that had caused cancer in humans or animals. Congress intervened after public opposition to the ban and allowed saccharin to remain in the food supply as long as the label carried this warning: "Use of this product may be hazardous to your health. This product contains saccharin which has been determined to cause cancer in laboratory animals." Further research was required to confirm the tumor findings.

Since then, more than 30 human studies have been completed and found that the results found in rats did not translate to humans, making saccharin safe for human consumption. The original study published in 1977 has since been criticized for the very high dosages, that were hundreds of times higher than "normal" ingestion for humans, that were given to the rats. In 2000, the National Toxicology Program (NTP) of the National Institutes of Health concluded that saccharin should be removed from the list of potential carcinogens. The warning has now been removed from saccharin-containing products.



Next: Saccharin: What is the negative side? »

Printer-Friendly Format  |  Email to a Friend

Weight Loss Wisdom

Get tips, recipes and inspiration.


Are you Depressed? Take the Quiz

Your Guide to Symptoms & Signs: Pinpoint Your Pain












Health categories:

Slideshows | Diseases & Conditions | Symptoms & Signs | Procedures & Tests | Medications | Health & Living | News & Views | Medical Dictionary

Popular health centers:

Allergies | Arthritis | Cancer | Diabetes | Digestion | Healthy Kids | Heart | Men's Health | Mental Health | Women's Health | More...

Publications:

ePublications (PDFs) | XML News via RSS | Audio Podcasts | Email Newsletters

MedicineNet.com:

About Us | Privacy Policy | Site Map | WebMD® | Medscape® | eMedicine® | eMedicineHealth® | RxList®

This website is certified by Health On the Net Foundation. Click to verify. This site complies to the HONcode standard for trustworthy health information:
verify here.

©1996-2009 MedicineNet, Inc. All rights reserved. Notices and Legal Disclaimer.
MedicineNet does not provide medical advice, diagnosis or treatment. See additional information.