Carbamazepine (Tegretol), phenobarbital, and rifampin (Rifadin) may reduce the action of armodafinil by increasing armodafinil's elimination by the liver. Ketoconazole (Nizoral), itraconazole (Sporanox) and erythromycin may increase the effectiveness of armodafinil by reducing the elimination of armodafinil by the liver.
NURSING MOTHERS: It is not known whether armodafinil is secreted in breast milk.
Medically reviewed by Eni Williams, PharmD
Reference: FDA Prescribing Information for Nuvigil
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