PRECAUTIONS: Tell your doctor your medical history, especially of: liver problems, recent or current bleeding, stroke, recent surgery or injury, severe high blood pressure, certain stomach problems (e.g., ulcers), bleeding disorders or low platelet counts (thrombocytopenia), eye problems, any allergies. Tell your doctor if you are pregnant before using this medication. It is not known whether this drug passes into breast milk. Consult your doctor before breast-feeding.

DRUG INTERACTIONS: Tell your doctor of all prescription and nonprescription medication you may use, especially: other "blood thinning" medications (e.g., aspirin, clopidogrel, dipyridamole, heparin, ticlopidine, warfarin, NSAIDs such as ibuprofen, or thrombolytics such as alteplase). Argatroban has been used effectively in combination with certain other "blood thinners" such as aspirin or warfarin. Be sure to check with your doctor or pharmacist regarding which medicines you need to take after leaving the hospital. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include: persistent bleeding.

NOTES: Laboratory and/or medical tests (e.g., platelets, aPTT, hemoglobin, hematocrit, liver function tests) may be performed to monitor your progress.

MISSED DOSE: If your dose is stopped or interrupted, contact the doctor immediately to establish a new dosing schedule/rate.

STORAGE: Before mixing, store the vials at room temperature (77 degrees F or 25 degree C) away from light. Brief storage between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Do not freeze. After mixing/dilution with IV fluids, this product is stable for 24 hours at room temperature or 48 hours refrigerated (between 36 and 46 degrees F or 2 and 8 degrees C) away from light. Do not freeze the mixed solution.

MEDICAL ALERT: Your condition can cause complications in a medical emergency. For enrollment information call MedicAlert at 1-800-854-1166 (USA), or 1-800-668-1507 (Canada).