argatroban - injection
GENERIC NAME: ARGATROBAN - INJECTION (ar-GAH-troh-ban)
USES: Argatroban is a type of "blood thinner" used instead of heparin to prevent blood clots during certain procedures to open up the blood vessels in the heart (e.g., balloon angioplasty, coronary stent placement, percutaneous coronary intervention-PCI). It is usually used with aspirin. It is also used to treat and prevent harmful blood clots and increase platelets in patients who have had a reaction to heparin (e.g., heparin-induced thrombocytopenia-HIT).Argatroban works by blocking a certain natural substance (thrombin) that the body uses to form blood clots. Blood clots can cause a heart attack, stroke, gangrene, or cause the opened blood vessel in the heart to close back up.
HOW TO USE: Follow all instructions for proper mixing and dilution with the correct IV fluids. If you have questions about using this medication properly, consult your pharmacist.Before using this product, check it visually for particles or discoloration. If either is present, do not use the liquid.This medication is usually given by injection into a vein over 3 to 5 minutes (bolus dose) by a health care professional before your procedure. It is then given slowly into a vein (by infusion) during your procedure. More bolus doses may be given during the procedure. The infusion may be continued after your procedure as directed by your doctor.If you are being treated for a platelet problem (e.g., HIT), the drug is usually given slowly into a vein without a bolus dose or as directed by your doctor.The dosage is based on your weight, medical condition, and response to treatment. Your doctor will order blood-clotting tests to find the best dose for you.After your procedure, you will need to lie very still with your head up slightly. The tube for your procedure is usually placed near the groin. Keep the leg (or other limb nearest the tube) straight to prevent bleeding from the tube area. Pressure will be applied to the area (e.g., with a sandbag, special pressure dressing/device). You will not be allowed out of bed for several hours after the procedure.
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