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February 9, 2012
The Cleveland Clinic


Pain Management: Arachnoiditis

Arachnoiditis is a pain disorder caused by the inflammation of the arachnoid, one of the membranes that surround and protect the nerves of the spinal cord. It is characterized by severe stinging, "burning pain", and neurological problems.

Symptoms

Arachnoiditis has no consistent pattern of symptoms, but in many people it affects the nerves connecting to the lower back and legs. The most common symptom is pain; but, arachnoiditis can also cause:

  • Tingling, numbness, or weakness in the legs
  • Sensations that may feel like insects crawling on the skin or water trickling down the leg
  • Severe shooting pain that can be similar to an electric shock sensation
  • Muscle cramps, spasms and uncontrollable twitching
  • Bladder, bowel and/or sexual dysfunction

As the disease progresses, symptoms may become more severe or even permanent. Many people with arachnoiditis are unable to work and suffer significant disability because they are in constant pain.

Causes of Arachnoiditis

Inflammation of the arachnoid can lead to the formation of scar tissue and can cause the spinal nerves to stick together and malfunction. The arachnoid can become inflamed because of an irritation from one of the following sources:

  • Direct injury to the spine
  • Chemicals: Dye used in myelograms (diagnostic tests in which a dye called radiographic contrast media is injected into the area surrounding the spinal cord and nerves) have been blamed for some cases of arachnoiditis. The radiographic contrast media responsible for this is no longer used, however. Also, there is concern that the preservatives found in epidural steroid injections may cause arachnoiditis.
  • Infection from bacteria or viruses: Infections such as viral and fungal meningitis or tuberculosis can affect the spine.
  • Chronic compression of spinal nerves: Causes for this compression include chronic degenerative disc disease or advanced spinal stenosis (narrowing of spinal column).
  • Complications from spinal surgery or other invasive spinal procedures: Similar causes include multiple lumbar (lower back) punctures.



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