GENERIC NAME: apixaban
BRAND NAME: Eliquis
DRUG CLASS AND MECHANISM: Apixaban is an oral drug used treat and prevent blood clots (an anticoagulant or blood thinner) in the hearts of patients with atrial fibrillation. These clots are likely to break up into pieces that go to the brain and cause strokes.
Similarly, it is used to treat and prevent blood clots in the deep veins of the legs (deep venous thrombosis or DVT). These clots are likely to break up into pieces that go to the lungs and block the lung's arteries, i.e., a pulmonary embolus. Apixaban works by blocking the action of factor Xa. Factor Xa is an important protein in the coagulation cascade that causes blood to clot. Reducing the action of factor Xa reduces the ability of blood to clot. Apixaban was approved by the FDA on December 28, 2012.
PRESCRIBED FOR: Apixaban is used for reducing the risk of blood clots in the heart and strokes in patients with atrial fibrillation who have no problems with their heart valves (nonvalvular atrial fibrillation). It also is used for treating and preventing deep venous thrombosis (DVT) and pulmonary embolism.
SIDE EFFECTS: The most common side effects of apixaban involves bleeding in the:
- brain, and
Quick GuideAtrial Fibrillation: Heart Symptoms, Diagnosis & Treatment for AFib
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