Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.
Dr. Shiel received a Bachelor of Science degree with honors from the University of Notre Dame. There he was involved in research in radiation biology and received the Huisking Scholarship. After graduating from St. Louis University School of Medicine, he completed his Internal Medicine residency and Rheumatology fellowship at the University of California, Irvine. He is board-certified in Internal Medicine and Rheumatology.
How are the results of an antro-duodenal motility study
evaluated?
Normally, there are characteristic patterns of contraction of
the stomach and
duodenum during fasting periods and after meals. In patients
with motility problems of the stomach and/or small intestine, the
characteristic patterns are abnormal or completely absent. Such patients
may be treated with drugs to stimulate contraction,
such as metoclopramide (Reglan). Cisapride (Propulsid), however, has been removed
from the market because of adverse side effects.
Are there any side effects to an antro-duodenal motility study?
There are no important side effects; however, the tube
can become quite irritating after several hours, giving the patient a sore
throat. Occasionally, the tube also causes nasal irritation. Within
24 hours after the tube is removed, the irritation disappears.
Are there any alternatives to an antro-duodenal motility study?
Other tests can help with the evaluation of motility
disorders, including upper gastrointestinal X-rays,
gastric emptying studies,
and electrogastrograms. The most recent device for determining gastrointestinal
motility is a radiotelemetry capsule (Smartpill) that senses the pressure generated when the stomach or intestinal muscles contract around it. The capsule is swallowed, and it then travels through the stomach and intestines. While it is traveling, it continually senses the pressure around it and transmits this information wirelessly to a receiver worn on the outside of the body. Later, the data is downloaded from the recorder and analyzed.
Diabetes mellitus is a chronic condition characterized by high levels of sugar (glucose) in the blood. The two types of diabetes are referred to as type 1 (insulin dependent) and type 2 (non-insulin dependent). Symptoms of diabetes include increased urine output, thirst, hunger, and fatigue. Treatment of diabetes depends on the type.
Dyspepsia (indigestion) is a functional disease in which the gastrointestinal organs, primarily the stomach and first part of the small intestine, function abnormally. It is a chronic disease in which the symptoms fluctuate infrequency and intensity. Symptoms of dyspepsia include upper abdominal pain, belching, nausea, vomiting, abdominal bloating, early satiety, and abdominal distention (swelling). These symptoms are most often provoked by eating.
Gastroparesis is a medical condition in which the muscle of the stomach is paralyzed by a disease of either the stomach muscle itself or the nerves controlling the muscle. As a consequence, food and secretions do not empty normally from the stomach. Gastroparesis symptoms are nausea and vomiting; abdominal bloating, and pain can result.