Antihistamines (Oral) (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

Due to their significant side effect profile, special precautions should be used in patients with:

Second generation antihistamines are less sedating than their first generation counterparts. Cetirizine can be sedating for some patients at normal recommended doses while sedation seems to only be a concern with loratadine at higher than normally recommended doses. Fexofenadine is the least sedating.

Side effects common to all antihistamines include:

What drugs interact with oral antihistamines?

Antihistamines may cause drowsiness. Taking antihistamines with other medicines that also are sedating may cause profound drowsiness. Examples include:

Medically Reviewed by a Doctor on 7/9/2015

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