Type 2 Oral Diabetes Medications (Oral)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Jay W. Marks, MD
    Jay W. Marks, MD

    Jay W. Marks, MD

    Jay W. Marks, MD, is a board-certified internist and gastroenterologist. He graduated from Yale University School of Medicine and trained in internal medicine and gastroenterology at UCLA/Cedars-Sinai Medical Center in Los Angeles.

What are examples of oral diabetes medications available in the US?

α-glucosidase inhibitors


Sulfonylureas are grouped into two classes, first and second generation agents.

First generation sulfonylureas include

Second generation sulfonylureas are


The only biguanide available in the United States is metformin (Glucophage, Glucophage XR, Riomet).


Thiazolidinediones or TZDs include


DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors)

SGLT-2 inhibitors

Bile acid sequestrants

Currently the only bile acid sequestrant approved for the oral treatment of type 2 diabetes is colesevelam (Welchol).

Dopamine agonists

Bromocriptine mesylate (Cycloset) is a dopamine agonist.

What are examples of combination oral diabetes medications?

Combination oral diabetes drugs include

Medically Reviewed by a Doctor on 10/8/2015

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