Antidepressants (cont.)
What are examples of SSRIs?
What are serotonin norepinephrine reuptake inhibitors (SNRIs)?
SNRIs are the newest class of antidepressants. SNRIs work by increasing the
levels of serotonin and norepinephrine in the brain. Drug interactions and side
effects associated with SNRIs are similar to those seen with SSRIs.
SNRIs may
increase blood pressure, especially at high doses. High blood pressure caused by
SNRIs may be managed by reducing the dose of the SNRI.
What are examples of SNRIs?
Conclusion
Depression is a serious condition that often can be effectively treated with
available therapies. Many antidepressants have been developed over the years.
The newer classes of antidepressants are better tolerated and associated with
fewer drug interactions than the older class of antidepressants. Side effects
and drug interactions are barriers to successful treatment. Some side effects of
antidepressants resolve with continued use while other side effects can be
managed by dose reduction or adding other therapies. Appropriate management of
side effects and avoidance of drugs that may interact with antidepressants may
improve the success of antidepressant therapy.
Reference: FDA Prescribing Information
Last Editorial Review: 5/27/2009
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
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