anistreplase-injection, Eminase (cont.)

PRECAUTIONS: This drug should not be used when the following conditions are present: bleeding, blood vessel abnormalities, brain tumor, history of stroke, recent surgery, extremely high blood pressure (200/120 or higher). This drug should be used with caution when the following conditions exist: childbirth within the last 10 days, blood clotting problems, endocarditis, recent retinal bleeding, recent gastrointestinal or urinary tract bleeding, ulcers, very high blood pressure (180/110), a recent invasive procedure, if you have ever had a synthetic graft placed (knitted Dacron), heart abnormalities. This medication should be used during pregnancy only if clearly needed. Discuss the risks and benefits with your doctor.

DRUG INTERACTIONS: Tell your doctor of all prescription and nonprescription drugs you may use, especially of: corticosteroids (e.g., prednisone), aspirin (or drugs related to aspirin), "blood thinners" (e.g., warfarin, heparin), aminocaproic acid, drugs used for high blood pressure, valproic acid, injectable cephalosporins, drugs used for arthritis (NSAID such as ibuprofen and naproxen), sulfinpyrazone. Do not start or stop any medicine without doctor or pharmacist approval.

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