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anistreplase-injection, Eminase

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GENERIC NAME: ANISTREPLASE - INJECTION (an-ISS-treh-plays)

BRAND NAME(S): Eminase

Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage | Medical Alert

USES: This medication prevents blood from clotting. Studies have shown this medication to be effective in reducing the risk of death following an acute heart attack.

HOW TO USE: This medication is given by injection into a vein as soon as possible after heart attack symptoms occur. It will be given by a health care professional who will closely monitor your therapy.

SIDE EFFECTS: Bleeding and irregular heart rhythms may occur as a result of this drug. You will be monitored closely for signs of these effects. Notify your doctor of: itching, flushing, skin rash, fever, chills, headache, nausea, sweating, dizziness, muscle aches or tremor. If you notice other effects not listed above, contact your doctor or pharmacist.

PRECAUTIONS: This drug should not be used when the following conditions are present: bleeding, blood vessel abnormalities, brain tumor, history of stroke, recent surgery, extremely high blood pressure (200/120 or higher). This drug should be used with caution when the following conditions exist: childbirth within the last 10 days, blood clotting problems, endocarditis, recent retinal bleeding, recent gastrointestinal or urinary tract bleeding, ulcers, very high blood pressure (180/110), a recent invasive procedure, if you have ever had a synthetic graft placed (knitted Dacron), heart abnormalities. This medication should be used during pregnancy only if clearly needed. Discuss the risks and benefits with your doctor.

DRUG INTERACTIONS: Tell your doctor of all prescription and nonprescription drugs you may use, especially of: corticosteroids (e.g., prednisone), aspirin (or drugs related to aspirin), "blood thinners" (e.g., warfarin, heparin), aminocaproic acid, drugs used for high blood pressure, valproic acid, injectable cephalosporins, drugs used for arthritis (NSAID such as ibuprofen and naproxen), sulfinpyrazone. Do not start or stop any medicine without doctor or pharmacist approval.

Report Problems to the Food and Drug Administration   You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088. Need help identifying pills and medications? Use the pill identifier tool on RxList.