PRECAUTIONS: Before taking this, tell your doctor your medical history, especially of: bleeding problems (ulcers or lengthy or heavy menstrual periods), diabetes, thyroid disease, liver disease, kidney disease, high blood pressure, heart disease, infections, recent surgery, allergies (especially drug allergies). If you have an illness that causes vomiting, diarrhea or fever for more than a few days, contact your doctor as the effects of this drug may be changed. Avoid sudden or drastic changes in your diet or alcohol consumption. Especially avoid eating large amounts of foods or vitamin supplements rich in vitamin K (leafy green vegetables, green beans, broccoli, liver, some cheeses). Anisindione is not recommended for use during pregnancy. Consult your doctor before using this medication. This drug may be excreted into breast milk. Consult your doctor before breast-feeding. It is important that all doctors, dentists and health care professionals caring for you know you are taking this so they can avoid prescribing other medications that may interfere with its effect.

DRUG INTERACTIONS: Many medications can increase or decrease the effect of this drug. Tell your doctor of all nonprescription and prescription drugs you are taking particularly of: aspirin, antibiotics, seizure medication, thyroid medication, drugs used for sleeping, anti-ulcer drugs, vitamins and nutritional supplements, dong quai, ginkgo biloba, ginseng. Do not start or stop any medicine without doctor or pharmacist approval.

OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include bleeding, fast heartbeat, nausea, vomiting, stomach pain, diarrhea, and discoloration of urine or stools.

NOTES: Lab tests will be done periodically while taking this to monitor its effects and prevent side effects. While taking this, be extra careful to avoid injuries as this can cause easy bleeding. Use an electric razor and gently brush your teeth.

Report Problems to the Food and Drug Administration You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088. Need help identifying pills and medications? Use the pill identifier tool on RxList.