anakinra, Kineret (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

PRESCRIBED FOR: Anakinra is used for treating the signs and symptoms of moderate to severe rheumatoid arthritis in individuals 18 years of age or older. It is not a first-line drug but is used in individuals who have failed at least one of the other disease-modifying drugs that are used to treat rheumatoid arthritis. It can be used alone or in combination with other agents, but it should not be used with drugs that block tumor necrosis factor alpha such as infliximab (Enbrel) and etanercept (Remicade). (See drug interactions.)

Anakinra also is for used for treatment of neonatal-onset multisystem inflammatory disease (NOMID) due to cryopyrin-associated periodic syndromes (CAPS).

SIDE EFFECTS: The most common side effects are reactions at the site of injection, for example, redness, swelling and pain.

Other minor side effects include:

The most serious side effects are an increase in infections and a decrease in the number of white blood cells (neutropenia) and platelets.

Anakinra should not be started in individuals with active infections.

Infections occur more frequently when anakinra is used in combination with drugs that block tumor necrosis factor.

Medically Reviewed by a Doctor on 12/15/2014


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