- What is anakinra?
- Is anakinra available as a generic drug?
- Do I need a prescription for anakinra?
- Why is anakinra prescribed to patients?
- What are the side effects of anakinra?
- What is the dosage for anakinra?
- Which drugs or supplements interact with anakinra?
- Is anakinra safe to take during pregnancy or while breastfeeding?
- What else should I know about anakinra?
What is anakinra?
Anakinra (Kineret) is a synthetic (man-made), injectable, interleukin-1 (IL-1) receptor antagonist that blocks the effects of human interleukin-1. It is used in the treatment of rheumatoid arthritis.
Is anakinra available as a generic drug?
Do I need a prescription for anakinra?
Why is anakinra prescribed to patients?
Anakinra is used for treating the signs and symptoms of moderate to severe rheumatoid arthritis in individuals 18 years of age or older. It is not a first-line drug but is used in individuals who have failed at least one of the other disease-modifying drugs that are used to treat rheumatoid arthritis. It can be used alone or in combination with other agents, but it should not be used with drugs that block tumor necrosis factor alpha such as infliximab (Enbrel) and etanercept (Remicade). (See drug interactions.)
Anakinra also is for used for treatment of neonatal-onset multisystem inflammatory disease (NOMID) due to cryopyrin-associated periodic syndromes (CAPS).
What are the side effects of anakinra?
The most common side effects are reactions at the site of injection, for example, redness, swelling and pain.
Other minor side effects include:
The most serious side effects are an increase in infections and a decrease in the number of white blood cells (neutropenia) and platelets.
Anakinra should not be started in individuals with active infections.
Infections occur more frequently when anakinra is used in combination with drugs that block tumor necrosis factor.
Quick GuideRheumatoid Arthritis (RA) Symptoms & Treatment
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