Amyotrophic Lateral Sclerosis Index

Featured: Amyotrophic Lateral Sclerosis (ALS) Main Article

Amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease) is a neurological disease that progresses rapidly. The disease attacks the nerve cells responsible for the control of voluntary muscles. Early symptoms include cramping, twitching, or stiffness of the muscles; slurred nasal speech; difficulty swallowing or chewing, and muscle weakness in an arm or leg. Currently, the cause of ALS is not known. ALS is a fatal disease. No cure has been found for ALS, however, the drug riluzole (Rilutek) is FDA approved, and this drug reduces the damage to motor neurons by decreasing the release of glutamate.

Patient Discussions - Viewers share their comments

Medications

    Related Diseases & Conditions

    • Liver (Anatomy and Function) The liver is the largest gland and organ in the body. There are a variety of liver diseases caused by liver inflammation,...learn more »
      In This Article
      Liver (Anatomy and Function) Article
      • What is the liver? Is it a gland or an organ?
      • What is the functional purpose of the liver?
      • What does the liver look like, and where is it located in the body?
      • What diseases affect the liver?
      • Fatty liver disease
      • Cirrhosis
      • Infections
      • Hepatitis
      • Medications
      • Toxins
      • Genetic disorders
      • Cancer
      • Abnormalities of bile flow from the liver
      • Decrease in blood flow draining from the liver
      • What are symptoms of diseases of the liver?
      • How is an examination of the liver performed?
      • What is a liver biopsy?
      • Can diseases of the liver be prevented?
    • Human Immunodeficiency Virus (HIV) The human immunodeficiency virus (HIV) causes HIV infection and the acquired immunodeficiency syndrome (AIDS). Symptoms and signs...learn more »
      In This Article
      Human Immunodeficiency Virus (HIV) Article
      • Human immunodeficiency virus (HIV) facts
      • What is the history of HIV, and when was HIV discovered?
      • What tests are used in the diagnosis of HIV?
      • How is HIV spread (transmitted)?
      • What are symptoms and signs of HIV infection and AIDS in men, women, and children?
      • What happens after an exposure to the blood or genital secretions of an HIV-infected person?
      • What laboratory tests are used to monitor HIV-infected people?
      • What are HIV treatments and medications? What are the key principles in managing HIV infection?
      • When should antiviral therapy be started?
      • What is the initial therapy for HIV?
      • What are nucleoside and nucleotide analogue reverse transcriptase inhibitors (NRTIs)?
      • What are nonnucleoside analogue reverse transcriptase inhibitors (NNRTIs)?
      • What are protease inhibitors?
      • What are fusion inhibitors?
      • What is a CCR5 antagonist?
      • What is an integrase strand transfer inhibitor?
      • What HIV drugs are in development?
      • What are side effects of HIV therapy?
      • What happens if the patient's viral load increases while on HIV therapy?
      • What are the risks of missing doses or stopping antiviral therapy?
      • Should patients with the flu- or mono-like illness of primary HIV infection be treated?
      • What about treatment for HIV during pregnancy?
      • What can be done for people who have severe immunosuppression?
      • What is the future for HIV-infected individuals with regards to treatment simplification and cure research?
      • What is in the future for preventing HIV transmission?
    • Constipation Constipation is defined medically as fewer than three stools per week and severe constipation as less than one stool per week....learn more »
    • Depression Depression is an illness that involves the body, mood, and thoughts and affects the way a person eats and sleeps, the way one...learn more »
      In This Article
      Depression Article
      • Depression facts
      • What is a depressive disorder?
      • What are myths about depression?
      • What are the types of depression, and what are depression symptoms and signs?
      • Depression symptoms and signs in men
      • Depression symptoms and signs in women
      • Depression symptoms and signs in teenagers
      • Depression symptoms and signs in children
      • What are the risk factors and causes of depression?
      • Postpartum depression
      • How is depression diagnosed?
      • What treatments are available for depression?
      • What is the general approach to treating depression?
      • What about sexual dysfunction related to antidepressants?
      • What about discontinuing antidepressants?
      • What are complications of depression?
      • What is the prognosis for depression?
      • How can depression be prevented?
      • What about self-help and home remedies for depression?
      • How can someone help a person who is depressed?
      • Where can one seek help for depression?
      • What is in the future for depression?
      • Where can people find more information about depression?
    • Lyme Disease Lyme disease is a bacterial illness, which is spread by ticks when they bite the skin. Initially the disease affects the skin...learn more »
    • Multiple Sclerosis (MS) Multiple sclerosis or MS is an autoimmune disorder in which brain and spinal cord nerve cells become demyelinated. This damage...learn more »

Related FAQs, Doctor's & Expert's Views

Health & Living

Procedures & Tests

Health News

Health Features

Tools & References

FDA Drug Labels on RxList.com


Terms related to Amyotrophic Lateral Sclerosis:

  • ALS
  • Lou Gehrig's Disease