amprenavir - oral, Agenerase (cont.)

HOW TO USE: Read the Patient Information Leaflet provided by your pharmacist before you start taking amprenavir and each time you get a refill. If you have any questions regarding the information, consult your doctor or pharmacist.Take this medication by mouth with or without a meal (low-fat) or up to 2 hours after a meal, usually 2 times daily or as directed by your doctor.The dosage is based on your weight, liver function, medical condition, other medications, and response to therapy.It is very important to continue taking this medication (and other HIV medications) exactly as prescribed by your doctor.This medication works best when the amount of drug in your body is kept at a constant level. Therefore, take this drug at evenly spaced intervals. To help you remember, take it at the same times each day.Do not take more or less of this drug than prescribed or stop taking it (or other HIV medicines) even for a short time unless directed to do so by your doctor. Skipping or changing your dose without approval from your doctor may cause the amount of virus to increase, make the infection more difficult to treat (resistant), or worsen side effects.This medication contains vitamin E to help preserve the amprenavir. Do not take any other vitamin E supplements unless directed to do so by your doctor because too much vitamin E can cause health problems.If you are taking antacids (including didanosine dispersible tablets /solution), take amprenavir at least 1 hour before or after the antacid.The capsule and liquid forms of amprenavir are not equal in strength. Do not switch forms without consulting your doctor or pharmacist.

SIDE EFFECTS: See also Warning section.Diarrhea, nausea, vomiting, heartburn, stomach pain, gas, loss of appetite, headache, tiredness, strange taste in the mouth, or tingling/numbness of hands/feet/mouth area may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.Tell your doctor immediately if any of these unlikely but serious side effects occur: persistent nausea, stomach/abdominal pain, dark urine, yellowing eyes/skin, decreased sexual interest, mental/mood changes (e.g., depression, anxiety), increasing tiredness, increased urination (especially at night), increased thirst, fruity breath odor.Seek immediate medical attention if any of these rare but serious side effects occur: symptoms of a heart attack (such as chest/jaw/left arm pain, shortness of breath, unusual sweating), severe tiredness, fainting, pale lips/nails/skin, fast heartbeat, fast breathing.Changes in body fat may occur while you are taking this medication (e.g., increased fat in the upper back and stomach areas, decreased fat in the arms and legs). The cause and long-term effects of these changes are unknown. Discuss the risks and benefits of therapy with your doctor, as well as the possible role of exercise to reduce this side effect.If you are taking HIV medications for the first time, you may experience symptoms of an old infection. This may happen as your immune system begins to work better. Contact your doctor immediately if you notice any of the following symptoms: new cough, trouble breathing, fever, new vision problems, new headaches, new skin problems.A very serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

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