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February 10, 2012

ampicillin, Omnipen, Polycillin, Principen (cont.)

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SIDE EFFECTS: Common side effects of ampicillin include nausea, vomiting, loss of appetite, diarrhea, abdominal pain, rash, itching, headache, confusion and dizziness. Patients with a history of allergic reactions to other penicillins should not receive ampicillin. Persons who are allergic to the cephalosporin class of antibiotics, which are related to the penicillins, for example, cefaclor (Ceclor), cephalexin (Keflex), and cefprozil (Cefzil), may or may not be allergic to penicillins. Serious but rare reactions include seizures, severe allergic reactions (anaphylaxis), and low platelet or red blood cell count. Ampicillin can alter the normal bacteria in the colon and encourage overgrowth of some bacteria such as Clostridium difficile which causes inflammation of the colon (pseudomembranous colitis). Patients who develop signs of pseudomembranous colitis after starting ampicillin (diarrhea, fever, abdominal pain, and possibly shock) should contact their physician immediately.

Reference: FDA Prescribing Information


Last Editorial Review: 1/9/2009



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