amphotericin injection (cont.)
PRECAUTIONS: Tell your doctor your medical history, especially of: heart disease, liver disease, kidney disease, any allergies. This medication should be used only if clearly needed during pregnancy. Use of this medication is not recommended while breast-feeding. Discuss the risks and benefits with your doctor.
DRUG INTERACTIONS: Tell your doctor of any nonprescription or prescription medication you may take particularly: steroids (e.g., prednisone), digoxin, cyclosporine, anti-cancer medications, other anti-fungal drugs, tacrolimus. Do not start or stop any medicine without doctor or pharmacist approval.
OVERDOSE: If overdose is suspected, contact your local poison control center or emergency room immediately. US residents can call the US national poison hotline at 1-800-222-1222. Canadian residents should call their local poison control center directly. Symptoms of overdose may include dizziness, unusually slow heartbeat, or seizures.
NOTES: This medication is usually first given in a hospital setting where your condition and response can be closely monitored. Laboratory tests and blood counts will be done routinely while taking this to monitor its effects and prevent side effects.
MISSED DOSE: It is important to use each dose as scheduled. If you miss a dose, contact your health care provider who will help establish a new dose schedule. Do not "double-up" the dose to catch up.
STORAGE: Unopened vials should be refrigerated. Once prepared, the reconstituted vial (of concentrated solution 5mg/ml) may be refrigerated for up to 7 days. At room temperature it is stable for only 24 hours and must be protected from light. Solutions diluted for infusion (0.1mg/ml or less) should be used promptly after mixing and should be protected from light during administration. Check the expiration date on the label and properly discard of any unused medication after that time.
Last Editorial Review: 3/2/2005
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