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GENERIC NAME: AMPHOTERICIN INJECTION (am-foh-TAIR-eh-sin)

BRAND NAME(S): Amphocin, Fungizone

Warning | Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage

WARNING: Amphotericin should be used to treat only serious fungal infections. Do not use this medication for less severe infections such as oral thrush (white spots in the mouth), vaginal yeast infections, throat infections (esophageal), nor for localized (not spread throughout the body) fungal infections in people with a normal white blood count.

USES: This medication is used to treat a fungal infection.

HOW TO USE: This medication is administered by infusion into a vein by a health care professional. It is usually given once a day or every other day. It may be necessary to continue therapy with this medication for several weeks to months in certain cases. Stopping therapy too soon may result in ineffective treatment.

SIDE EFFECTS: Fever and chills may occur 1 to 2 hours after the infusion is started. This is more common with the first few doses and should subside as therapy continues. Nausea, vomiting, diarrhea, weakness, muscle aches, headache and irritation at the injection site may also occur. To help minimize these effects, you may be given a pain reliever or other medication before each dose. If these effects persist or worsen, notify your doctor promptly. Notify your doctor promptly if you experience: irregular or rapid heartbeat, severe weakness, vision changes, tingling of the hands or feet, ringing in the ears, trouble urinating. In the unlikely event you have an allergic reaction to this drug, seek medical attention immediately. Symptoms of an allergic reaction include: rash, itching, swelling, dizziness, trouble breathing. If you notice other effects not listed above, contact your doctor or pharmacist.




Report Problems to the Food and Drug Administration

 

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.


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amphotericin injection, Amphocin, Fungizone

What is histoplasmosis?

Histoplasmosis is a disease, usually affecting the lungs, caused by the Histoplasma capsulatum fungus. Although many people that are or have been infected with H. capsulatum do not appear ill, some people in the acute phase of the disease have a dry cough, fever, and chest pains and do feel ill. There are several types of histoplasmosis (acute, chronic, and disseminated, all with subtypes).

H. capsulatum was first described by Samuel Darling in 1906 within human tissue cells (histiocytes). In 1932, Katharine Dodd and Edna Tompkins made the first diagnosis of histoplasmosis in an infant. Since the 1930s, H. capsulatum has been found worldwide, but the majority of cases are found in river valleys in temperate regions of the world and in equatorial Africa (in Africa, H. capsulatum has a variant thick-walled yeast form termed H. duboisii). Often an outbreak occurs in a group of ...

Read the Histoplasmosis article »



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