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Medication Written by Pharmacists Reviewed by Doctors

GENERIC NAME: amphetamine and dextroamphetamine

BRAND NAME: Adderall, Adderall XR

DRUG CLASS AND MECHANISM: Amphetamine and dextroamphetamine are used in combination to treat attention-deficit hyperactivity disorder (ADHD) and narcolepsy. Adderall stimulates the brain and also can increase blood pressure. In a recent small study in children with ADHD, the effects of Adderall lasted longer and were preferred over methylphenidate (Ritalin), the most commonly used drug for ADHD. Adderall XR is an extended release form of Adderall.  Adderall was approved by the FDA in 1996.

GENERIC AVAILABLE: no

PRESCRIPTION: yes

PREPARATIONS: Adderall tablets: 5, 7.5, 10, 12.5, 20, and 30 mg.  Adderall XR capsules: 5, 10, 15, 20, 25, and 30 mg.

STORAGE: Tablets should be stored at room temperature, between 15 and 30 °C (59-86 °F).

PRESCRIBED FOR: Adderall is used for the treatment of attention-deficit hyperactivity disorder (ADHD) and narcolepsy.

DOSING: Adderall usually is taken once or twice a day. Adderall XR is taken once daily.  The dose is adjusted carefully by the physician to achieve the desired effects.

DRUG INTERACTIONS: Adderall should not be taken with monoamine oxidase (MAO) inhibitor drugs including phenelzine (Nardil) and tranylcypromine (Parnate). Patients receiving antihypertensive medications may experience loss of blood pressure control with Adderall.

PREGNANCY: Adderall should not be used in pregnancy.

NURSING MOTHERS: Mothers taking amphetamines such as Adderall should refrain from nursing their infants because these drugs are excreted in human milk and can have undesirable effects on the child.

SIDE EFFECTS: Side effects of Adderall include excessive stimulation of the nervous system leading to nervousness, restlessness, excitability, dizziness, headache, fear, anxiety, tremor, and even hallucinations and convulsions (seizures). Blood pressure and heart rate may increase, and patients may experience palpitations of the heart.






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Last Editorial Review: 4/17/1999 8:28:00 PM





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