amoxicillin and clavulanic acid, Augmentin, Augmentin XR (cont.)

Pharmacy Author:
Medical and Pharmacy Editor:

SIDE EFFECTS: Common side effects include abdominal discomfort, bloating, diarrhea, gas, headache, heartburn, nausea, and vomiting. Other side effects include bloody or prolonged diarrhea, easy bruising or bleeding, reversible hepatitis, rash, and allergic reactions. Serious but rare reactions include seizures, severe allergic reactions (anaphylaxis), and low platelet or red blood cell count. Antibiotics can alter the normal bacteria in the colon and encourage overgrowth of some bacteria such as Clostridium difficile which causes inflammation of the colon (pseudomembranous colitis). Patients who develop signs of pseudomembranous colitis after starting Augmentin (diarrhea, fever, abdominal pain, and possibly shock) should contact their physician immediately. Persons who are allergic to the cephalosporin class of antibiotics, which are related to the penicillins, for example, cefaclor (Ceclor), cephalexin (Keflex), and cefprozil (Cefzil), may or may not be allergic to penicillins.

Reference: FDA Prescribing Information


Last Editorial Review: 12/15/2011



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