ammonium lactate (Amlactin, Geri-Hydrolac, Lac-Hydrin, Lac-Lotion, LAC Cream, Al-12)

  • Pharmacy Author:
    Omudhome Ogbru, PharmD

    Dr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. He was a Professor of Pharmacy Practice and a Regional Clerkship Coordinator for the University of the Pacific School of Pharmacy from 1996-99.

  • Medical and Pharmacy Editor: Charles Patrick Davis, MD, PhD
    Charles Patrick Davis, MD, PhD

    Charles Patrick Davis, MD, PhD

    Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.

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GENERIC NAME: ammonium lactate

BRAND NAME: Amlactin, Geri-Hydrolac, Lac-Hydrin, Lac-Lotion, LAC Cream, Al-12

DRUG CLASS AND MECHANISM: Ammonium lactate is an anti-itch topical medication formulated from 12% lactic acid and ammonium hydroxide. Ammonium lactate hydrates the outermost skin layer and promotes skin moisturizing for a prolonged time. Ammonium lactate also prevents keratinization of epidermal skin layer, which keeps skin smoother and hydrated for a longer time. The FDA approved ammonium lactate in April 1985.

PRESCRIPTION: Yes

GENERIC AVAILABLE: Yes

PREPARATIONS: Ammonium lactate 12% is available in cream and lotion forms. Cream is available in 280 grams (two 140 grams tubes) and 385 gram bottle. Lotion is available in 225 gram and 400 gram bottles.

STORAGE: Store ammonium lactate cream and lotion between temperatures 15 C to 30 C (59 F to 86 F).

PRESCRIBED FOR: Ammonium lactate gives temporary relief from itching due to dry, scaly skin, and ichthyosis vulgaris (an inherited skin disorder).

DOSING:

  • Adults and children 2 years of age and older: Apply to affected area(s) twice daily, rub in thoroughly.
  • Children under 2 years of age: Consult a doctor.

DRUG INTERACTIONS: Ammonium lactate should be used with caution with other topical agents if applied to same areas, due to a higher risk of sensitivity to sun exposure.

PREGNANCY: There are no adequate studies done on ammonium lactate to determine safe and effective use in pregnant women.

NURSING MOTHERS: It is not known whether ammonium lactate enters breast milk; therefore, it is best to be cautious before using it in nursing mothers.

SIDE EFFECTS: Side effects of ammonium lactate are stinging, burning, redness, skin peeling, and darkening of skin.

REFERENCE: Lac-Hydrin cream, lotion – Prescribing Information.

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